Introduction of HPV testing for cervical cancer screening in Central America: the Scale-Up project
Publication date: Available online 2 April 2020Source: Preventive MedicineAuthor(s): Francesca Holme, Jose Jeronimo, Francisco Maldonado, Claudia Camel, Manuel Sandoval, Benito Martinez-Granera, Mirna Montenegro, Jacqueline Figueroa, Rose Slavkovsky, Kerry A. Thomson, Silvia de Sanjose, the Scale-Up project team
Authors: Lum C, Prenen H, Body A, Lam M, Segelov E Abstract INTRODUCTION: Anal cancer is a rare malignancy with increasing incidence, notably in women. This disease is highly associated with HPV infection and its incidence and mortality are currently rising. Most patients present with localized disease which has a high survival after definitive treatment with chemoradiation. For patients who develop metastatic disease or present with this de novo, survival is poor. AREAS COVERED: This review provides a summary of current literature on anal cancer. With a focus on women, this includes current epidemiological tre...
Conclusion: The incidence of C. trachomatis infection in the endocervical samples from these women can be considered high, which emphasizes the importance of measures designed to clarify and prevent this important STI.RESUMEN Introducci ón: Chlamydia trachomatis es uno de los principales agentes causantes de infecciones de transmisión sexual (ITS) en hombres y mujeres, pero el mayor impacto de la infección se produce en el aparato reproductor de las mujeres, causando, entre otros problemas, infertilidad. Objetivo: Calcular la incidencia de C. trachomatis detectada por la técnica de reacció...
Conclusions: Menopausal symptoms were prevalent in this population. Our data indicate that women are experiencing climacteric symptoms, but are overall unmotivated to address symptoms using HT. Factors such as symptom severity, fear of side effects, income level, or education level were not associated with acceptability of HT for premature menopause.
Publication date: Available online 28 May 2020Source: Preventive MedicineAuthor(s): Preet K. Dhillon, Benjamin Hallowell, Sutapa Agrawal, Arpita Ghosh, Awdhesh Yadav, Elizabeth Van Dyne, Virginia Senkomago, Shivani A. Patel, Deepika Saraf, Roopa Hariprasad, Neha Dumka, Ravi Mehrotra, Mona Saraiya
ConclusionsHPV vaccination and screening interventions may be cost effective in LMICs and potentially reduce the lifetime risk, economic burden, and associated mortality. However, it is important to consider the factors that influence the cost effectiveness of cervical cancer prevention interventions for better outcomes to be realised.
With great deal of interest we read the article entitled “Clinical outcomes of vaginectomy and laser ablation for the treatment of post-hysterectomy women with vaginal high-grade squamous intraepithelial lesions: A retrospective study.” by Shen et al which was recently published in your journal . It was quite interesting the finding that in the qui te large cohort of patients they found that vaginectomy compared with laser ablation resulted in better clinical outcomes (higher recurrence-free survival rate and progression-free survival rate) among vaginal high-grade squamous intraepithelial lesions who had a ...
CONCLUSION: Our result revealed that the frequency of EBV infection is higher in HISL than LSIL. Moreover, the amount of HPV load showed an elevated level among co-infected patients, which indicates that EBV might be an enhancing factor of disease progression. In contrast, HSV may not has a role as a co-factor in cervical lesions pathogenesis. PMID: 32458656 [PubMed - in process]
CONCLUSIONS: Interestingly, the result of our study indicates that women are less willing to undergo the cryotherapy procedure if they have good knowledge about the cryotherapy procedure and its importance in cervical cancer's prevention. Providing higher quality and more accessible health facilities with cryotherapy services are important in influencing women's willingness to receive cryotherapy. Family support, in the form of permission given by spouses, and if they accompanied the patient to seek cryotherapy care are observed as factors influencing women's willingness to have the procedure.. PMID: 32458651 [PubMed - in process]
CONCLUSION: TA is as acceptable and safe as cryotherapy in screen and treat setting. TA has the logistic advantages for the low-resourced settings as the machines are more portable, do not require costly refrigerant gas and battery-driven models are available. The cure rates for CIN 1+ lesions in our study were comparable between cryotherapy and TA. PMID: 32458647 [PubMed - in process]
CONCLUSION: Considering the economic and health benefits of all the strategies, our results suggested careHPV every 3 or 5 years and VIA/VILI every 1 or 3 years eventually were more appropriate as screening methods in rural China. PMID: 32458639 [PubMed - in process]