The Impact of Neoadjuvant Chemotherapy on Margin Re-excision in Breast-Conserving Surgery

ConclusionThe re-excision rate following NAC is almost twice that of patients who underwent primary operative management. Her2+  and triple-negative tumors have lower re-excision rates and may represent a selected cohort most suitable for BCS. Patients with invasive lobular carcinoma or ER+ disease have significantly higher rates of margin positivity, and these patients should be considered for a cavity shave during prim ary surgery to reduce the rates of re-excision.
Source: World Journal of Surgery - Category: Surgery Source Type: research