Meibomian Gland Dysfunction in a Hospital-Based Population in Central India
Purpose:
To estimate the prevalence of meibomian gland dysfunction (MGD) in a hospital-based population in India.
Methods:
This cross-sectional study screened 3410 subjects ≥20 years or older attending the outpatient department by systematic random sampling. The patients were subjected to a comprehensive eye examination, Ocular Surface Disease Index questionnaire, fluorescein tear film breakup time, Schirmer I test, lissamine green stain, lid margin changes, and meibomian gland expression. MGD was diagnosed when 1 or both of the following was present in at least 1 eye: reduced or absent meibum secretion and cloudy to inspissated toothpaste-like secretion on digital pressure over the eyelids.
Results:
The study included 570 subjects with a mean age of 49.3 ± 16.2 (20–84) years. MGD was diagnosed in 317 (55.61%) subjects, of whom 272 (47.7%) had only MGD and 45 (7.9%) had coexisting MGD and aqueous tear deficiency. The age-adjusted prevalence rate of MGD was 48.4% (95% confidence interval: 43.9–52.1). This rate increased significantly with age (P
Source: Cornea - Category: Opthalmology Tags: Clinical Science Source Type: research