Association between loop diuretic dose changes and outcomes in chronic heart failure: observations from the ESC ‐EORP Heart Failure Long‐Term Registry

ConclusionDiuretic dose was unchanged in 76% and decreased in 8.3% of outpatients with chronic HF. LD dose increase was associated with worse outcomes, while the LD dose decrease group showed a trend for better outcomes compared with the no ‐change group. Higher systolic blood pressure, and absence of (i) sleep apnoea, (ii) peripheral congestion, and (iii) moderate/severe mitral regurgitation were independently associated with successful dose decrease.

https://onlinelibrary.wiley.com/doi/abs/10.1002/ejhf.1796?af=R

Source: European Journal of Heart Failure - March 31, 2020 Category: Cardiology Authors: Chris J. Kapelios, C écile Laroche, Maria G. Crespo‐Leiro, Stefan D. Anker, Andrew J.S. Coats, Beatria Díaz‐Molina, Gerasimos Filippatos, Mitja Lainscak, Aldo P. Maggioni, Theresa McDonagh, Alexandre Mebazaa, Marco Metra, Brenda Moura, Tags: Research Article Source Type: research