Efficient diversification of GM3 gangliosides via late-stage sialylation and dynamic glycan structural studies with 19F solid-state NMR

Org. Biomol. Chem., 2020, Advance Article DOI: 10.1039/D0OB00437E, PaperMaina Takahashi, Junya Shirasaki, Naoko Komura, Katsuaki Sasaki, Hide-Nori Tanaka, Akihiro Imamura, Hideharu Ishida, Shinya Hanashima, Michio Murata, Hiromune Ando GM3 gangliosides have been synthesizedvia late-stage α-sialylation using a macro-bicyclic sialyl donor.19F solid-state NMR analysis of the C5-NHTFAc GM3 analog on a model membrane revealed the influence of cholesterol on glycan dynamics. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research