An American Dental Association Clinical Evaluators Panel survey.
CONCLUSIONS: The survey results suggest that dentists' comfort levels and perceived roles in discussing and administering the HPV vaccine vary. PRACTICAL IMPLICATIONS: There is a need to further define the role of dentists and their team members in the promotion and administration of the HPV vaccine. Resources for dentists and dental team members may be helpful to support professional education and communication about the HPV vaccine. PMID: 32222178 [PubMed - in process]
Long non‑coding RNA NNT‑AS1 knockdown represses the progression of gastric cancer via modulating the miR‑142‑5p/SOX4/Wnt/β‑catenin signaling pathway. Mol Med Rep. 2020 May 18;: Authors: Zhang J, Zhang K, Hou Y Abstract Patients with advanced gastric cancer (GC) have a poor prognosis with a median overall survival of 10‑12 months. Long non‑coding RNA nicotinamide nucleotide transhydrogenase‑antisense RNA1 (NNT‑AS1) and sex‑determining region Y‑related high mobility group box 4 (SOX4) have been reported to be associated with the progression of various types of cancer; howe...
In conclusion, this study developed and validated a prognostic scoring system for alcohol‑related HCC based on lncRNAs. PMID: 32468063 [PubMed - as supplied by publisher]
Authors: Che J, Wu P, Wang G, Yao X, Zheng J, Guo C Abstract The aim of the present study was to investigate the expression of spalt like transcription factor 4 (SALL4) in the three most common types of renal cell carcinomas (RCC) [clear cell RCC (ccRCC), papillary renal cell carcinoma (pRCC) and chromophobe RCC (chRCC)], and the association with the overall survival (OS) of patients. The Cancer Genome Atlas (TCGA) database and RCC samples were used to investigate the expression levels of the SALL4 gene and its association with the OS in the three types of RCC based on the analysis of the transcriptome, copy number...
Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1. Mol Med Rep. 2020 May 27;: Authors: Zhou F, Du C, Xu D, Lu J, Zhou L, Wu C, Wu B, Huang J Abstract Lung cancer is a devastating cancer with high morbidity and mortality. Ubiquitin‑specific protease (USP) is a type of deubiquitinating enzyme (DUB) that has been implicated in numerous cancers, including colorectal, myeloma and breast. In the present study, the expression of USP51 was determined in the lung cancer cell line A549 and cisplatin (a...
In conclusion, TCGA classification based on a Chinese population is the same as TCGA typing based on a European population in terms of proportion and clinical characteristics, but there are differences in gene amplification and gene mutation. ACRG molecular classification could be performed by IHC analysis and may be a valuable independent prognostic marker for patients with GC. PMID: 32468041 [PubMed - as supplied by publisher]
Human papillomavirus (HPV) causes cervical cancer, anal cancer, vulvar cancer, vaginal cancer, penile cancer and oropharyngeal cancer. SCC in the genital region in particular is recognized to be caused by HPV infection, and intraepithelial lesions of the penis and vulva are termed penile intraepithelial neoplasia (PIN) and vulvar intraepithelial neoplasia (VIN), respectively. Although SCC of the nail apparatus is recognized as being associated with high-risk HPVs, it is not well-known in general medicine, and its analysis has been insufficient.
Human papillomavirus (HPV) causes cervical cancer, anal cancer, vulvar cancer, vaginal cancer, penile cancer, and oropharyngeal cancer. Squamous cell carcinoma (SCC) in the genital region in particular is recognized to be caused by HPV infection, and intraepithelial lesions of the penis and vulva are termed penile intraepithelial neoplasia and vulvar intraepithelial neoplasia, respectively. Although SCC of the nail apparatus is recognized as being associated with high-risk HPVs, it is not well-known in general medicine, and its analysis has been insufficient.
Human papillomavirus (HPV) is the most common sexually transmitted infection in North America [1,2]. The oncogenic potential of HPV was first described in cervical cancer . More recently, the link between oropharyngeal squamous cell carcinoma (OPSCC) and oral HPV infection was established [4,5]. An estimated 72% of OPSCC cases are associated with HPV in North America . The incidence of OPSCC has been rising rapidly, and has overtaken cervical cancer to become the most common HPV-related cancer in the United States [6,7].
Human papillomavirus (HPV) is a sexually transmitted infection that causes most oropharyngeal cancer cases in the United States [1,2]. While there are over 100 types of HPV, only 13 are considered carcinogenic, most notably HPV16 . The proportion of oropharyngeal cancers in the U.S. that are caused by HPV has increased from approximately 20% in 1990 to more than 70%, and the incidence of HPV-related oropharyngeal squamous cell carcinoma (HPV-OPSCC) has increased 225% over the past 20 years .
Squamous cell cancers of the head and neck as a group represent the sixth most common malignancy worldwide . While the overall incidence of head and neck cancers (HNC) at various anatomic subsites such as the ventrolateral tongue and floor of mouth has decreased in conjunction with reduced smoking and drinking rates, oropharyngeal squamous cell carcinomas (OPSCC) have increased mainly due to high-risk human papillomavirus (HPV) infection . HPV is a sexually transmitted infection, and currently recognized as the most prevalent sexually transmitted infection in the United States .
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