Virulence factors in coagulase-positive staphylococci of veterinary interest other than Staphylococcus aureus.

Virulence factors in coagulase-positive staphylococci of veterinary interest other than Staphylococcus aureus. Vet Q. 2020 Mar 30;:1-26 Authors: González-Martín M, Alberto Corbera J, Suárez-Bonnet A, Tejedor-Junco MT Abstract Coagulase-positive Staphylococci (CoPS) can exist as commensals in humans, companion and food-producing animals, but can cause severe or even lethal diseases. Exchange of these bacteria between humans and animals has been described. Special attention has been focused on Methicillin-Resistant Staphylococcus aureus, but other CoPS can also represent an important threat. In addition to significant antimicrobial resistance, these bacteria may carry a plethora of virulence factors - molecules that allow bacteria to establish on or within a host and increase their ability to cause disease. These virulence factors have been widely described in S. aureus but information about other species of CoPS is scarce. The aim of this paper is to review the recent literature about the virulence factors of non-aureus CoPS of animal origin. Their possible effects on human health are also described. The role and prevalence of different virulence factors including leukocidins, hemolysins, adhesins, enterotoxins, exfoliative and toxic shock syndrome toxins as well as superantigen-like proteins are addressed. The effect of these virulence factors on human health is also described. The possibility of misdiagnosis of species of CoPS ha...
Source: Veterinary Quarterly - Category: Veterinary Research Tags: Vet Q Source Type: research