A correlation analysis between clinical manifestations, therapeutic strategies and prognosis of children with cryptococcal meningitis in China

Cryptococcus meningitis (CM) is a subacute or chronic deep fungal infection of central nervous system, which is the most severe clinical manifestation caused by cryptococcus (Mpoza et al., 2019). The epidemiological data of the foreign countries show that the acquired immunodeficiency syndrome (AIDS) - related CM is more common (Bennett et al., 1979; Dismukes et al., 1987; Pappas et al., 2001; Mirza et al., 2003; Dromer et al., 2007 ), but the epidemiological data in China show that 50-77% of patients with CM have normal immune function (Lu et al., 1999; Kombila et al., 2016; Yao et al., 2005; Lui et al., 2006; Zhu et al., 2010; ), which suggested that Chinese CM patients have a certain particularity.

Source: International Journal of Infectious Diseases - March 30, 2020 Category: Infectious Diseases Authors: Haiyan Yang, Fei Yin, Ting Xiao, Siyi Gan, Zou Pan, Jing Peng, Liwen Wu Source Type: research