The Cause of the Bleeding and Thrombosis in Patients with Implanted Left Ventricular Assist Devices

Chronic heart failure (CHF) is one of the most severe and adverse diseases of the cardiovascular system, which requires heart transplantation (HT) for patient. Implantation of the left ventricular assist device (LVAD) is the treatment option instead of HT. LVAD can be implanted as a bridge to transplantation and destination therapy (DT). Unfortunately, DT of the LVAD has side effects such as bleeding and thrombosis. These side effects occur because of the non-physiological high shear stress of the LVAD, which causes platelet degradation.

Source: The Journal of Heart and Lung Transplantation - March 31, 2020 Category: Transplant Surgery Authors: M.R. Zhalbinova, S.E. Rakhimova, M.S. Bekbosynova, S.A. Andosova, B.U. Abdirova, A.R. Akilzhanova Tags: (1003) Source Type: research