Hybrid Thrombolysis for Left Ventricular Assist Device Thrombosis

LVAD thrombolysis can be effective but carries a bleeding risk. Existing data suggest intraventricular (vs peripheral) delivery may reduce bleeding, but is associated with early recurrence. We have developed a novel hybrid thrombolytic approach (hTL) using an initial high dose LV delivery of alteplase followed by a maintenance LV infusion.

Source: The Journal of Heart and Lung Transplantation - March 31, 2020 Category: Transplant Surgery Authors: A. Morley-Smith, E. Boey, J. Cannon, V. Rial Baston, F. Riesgo Gil, A. Simon, H. Lyster, O. Dar Tags: (1004) Source Type: research