Post-Discharge Quality of Life in Patients Receiving a Long-Term Ventricular Assist Device: Focus on Anxiety, Depression and Post Traumatic Stress Disorder

Reported outcomes after left ventricular assist device (LVAD) implant include mortality, hospital readmission and severe adverse events. We have less information about patients ’ perceptions of their quality of life (QOL) after hospital discharge. We conducted a prospective two-center international pilot study to assess anxiety, depression and post-traumatic stress disorder (PTSD) following LVAD implant as bridge to transplant (BTT) or destination therapy (DT).
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: (1105) Source Type: research

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OBJECTIVE: Psychological distress impacts a variety of health outcomes in hematopoietic stem cell transplantation (HSCT). Focused qualitative studies on a wider range of psychological distress in HSCT patients are lacking. However, understanding the subtle...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Conditions:   COVID-19;   SARS-CoV-2 Infection Interventions:   Diagnostic Test: Lung Function tests;   Diagnostic Test: Exercise capacity;   Diagnostic Test: Exercise physiology;   Diagnostic Test: Health-related quality of life;   Diagnostic Test: Respiratory symptoms, symptoms of anxiety and depression, and post-traumatic stress screeni ng Sponsors:   Federal University of Rio Grande do Sul;   Hospital de Clinicas de Porto Alegre;   Conse...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
In this study, we demonstrated that amitriptyline, a classic tricyclic antidepressant, reduced sepsis-induced brain damage through the tropomyosin receptor kinase A (TrkA) signaling pathway. Amitriptyline ameliorated neuronal loss assessed by Nissl staining in a mouse cecal ligation and puncture (CLP) –induced sepsis model. Furthermore, amitriptyline reduced early gliosis assessed by immunofluorescence and late cognitive deficits assessed by the Morris water maze (MWM) test. Moreover, amitriptyline treatment attenuated oxidative stress indicated by less superoxide dismutase (SOD) and catalase ( CAT) activity consumpt...
Source: Journal of Molecular Neuroscience - Category: Neuroscience Source Type: research
AbstractPost-traumatic stress disorder (PTSD) is a prevalent and debilitating illness. While standard treatment with pharmacotherapy and psychotherapy may be effective, approximately 20 to 30% of patients remain symptomatic. These individuals experience depression, anxiety, and elevated rates of suicide. For treatment-resistant patients, there is a growing interest in the use of neuromodulation therapies, including transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), and deep brain stimulation (DBS). We conducted a systematic review on the use of neuromodulation strategies for PTSD and p...
Source: Neurotherapeutics - Category: Neurology Source Type: research
CONCLUSION: The prevalence of psychiatric disorders among NKD was quite higher than in the general population of South Korea. PMID: 32450622 [PubMed - as supplied by publisher]
Source: Psychiatry Investigation - Category: Psychiatry Tags: Psychiatry Investig Source Type: research
CONCLUSION: Lung function abnormalities, psychological impairment and reduced exercise capacity were common in SARS and MERS survivors. Clinicians should anticipate and investigate similar long-term outcomes in COVID-19 survivors. PMID: 32449782 [PubMed - as supplied by publisher]
Source: Journal of Rehabilitation Medicine - Category: Rehabilitation Tags: J Rehabil Med Source Type: research
(Washington State University) Depression, anxiety and PTSD might not be disorders at all, according to a recent paper by Washington State University biological anthropologists. In the paper, the researchers propose a new approach to mental illness that would be informed by human evolution, noting that modern psychology, and in particular its use of drugs like antidepressants, has largely failed to reduce the prevalence of mental disorders.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news
ConclusionKnowledge of key factors for MDD, GAD and PTSD may be helpful for policy makers when formulating population level social and clinical programs, to mitigate the mental health effects of future natural disasters.
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
The global novel coronavirus pandemic afflicting everyone is showing mixed signs of activity. In some countries it appears to be easing, while in others it appears to be experiencing a resurgence. It’s not at all clear when the pandemic will end, but it’s unlikely to do so before 2021. What has become increasingly clear is that the toll of the pandemic will impact more than the people who come down with COVID-19. The mental health impact of living with a pandemic is being mostly ignored — for now. But as the deaths continue to rise, we need to pay close attention to the cost of the pandemic’s reperc...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General Grief and Loss Health-related Mental Health and Wellness Policy and Advocacy coronavirus COVID-19 Source Type: blogs
CONCLUSIONS: Trials of antidepressants may be driven mainly by commercial interests, focusing on prevalent diseases and everyday problems. No one can live a full life without experiencing several of the problems for which these drugs were tested. Antidepressants, sometimes called happy pills, could be seen as the modern version of Aldous Huxley's soma pill intended to keep everyone happy in the "Brave New World". PMID: 32444565 [PubMed - as supplied by publisher]
Source: International Journal of Risk and Safety in Medicine - Category: Drugs & Pharmacology Tags: Int J Risk Saf Med Source Type: research
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