5-Year Outcome of Patients Weaned off Corticosteroids after Heart Transplantation: Is There a Downside?

A large number of heart transplant patients are weaned off corticosteroids within the first year after heart transplantation. These patients are selected as they do not have rejection or graft dysfunction. In addition, these patients have not developed donor-specific antibodies (DSAs) and therefore are viewed as being immune-privileged. However, it has not been well established whether these patients have enhanced 5-year outcome compared to patients who remain on prednisone.

Source: The Journal of Heart and Lung Transplantation - March 31, 2020 Category: Transplant Surgery Authors: J. Patel, M. Kittleson, D.H. Chang, K. Nishihara, A. Shen, R. Sharoff, A. Velleca, B. Coleman, A. Hage, L. Czer, D. Ramzy, J.A. Kobashigawa Tags: (666) Source Type: research