Cardiac Cirrhosis is Largely Underdiagnosed by Non-Invasive Diagnostic Imaging Tests: A Retrospective Study

Hepatic cirrhosis is a potential severe complication of chronic heart failure and has major implications on treatment options. In general, patients with cirrhosis are considered ineligible for isolated cardiac transplantation. Therefore, proper diagnosis of cirrhosis is paramount. The aim of this retrospective study is to explore the diagnostic value of abdominal ultrasound, hepatosplenic scan and abdominal computed tomography scan (CT scan) for liver disease secondary to advanced heart failure.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: (564) Source Type: research

Related Links:

Abstract Decompensated cirrhosis is a condition associated with significant morbidity and mortality. While there have been significant efforts to develop quality metrics that ensure high-value care of these patients, wide variations in clinical practice exist. In this opinion review, we discuss the quality gap in the care of patients with cirrhosis, including low levels of compliance with recommended cancer screening and other clinical outcome and patient-reported outcome measures. We posit that innovations in telemedicine and mobile health (mHealth) should play a key role in closing the quality gaps in liver dise...
Source: World Journal of Gastroenterology : WJG - Category: Gastroenterology Authors: Tags: World J Gastroenterol Source Type: research
In conclusion, with study of the frailty syndrome still in its infancy, frailty analysis remains a major challenge. It is a challenge that needs to be overcome in order to shed light on the multiple mechanisms involved in the pathogenesis of this syndrome. Although several mechanisms contribute to frailty, immune system alteration seems to play a central role: this syndrome is characterized by increased levels of pro-inflammatory markers and the resulting pro-inflammatory status can have negative effects on various organs. Future studies should aim to better clarify the immune system alteration in frailty, and seek to esta...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Conclusion: In conclusion, liver cirrhosis is the major cause of ascites in Gondar, Ethiopia, while chronic viral hepatitis infections (hepatitis B (HBV) and C (HCV) viruses) are the main causes of liver cirrhosis. The other major causes included heart failure, tuberculosis, and hepatosplenic schistosomiasis. It is wise to consider and give priority to these diseases whenever one is evaluating a patient with ascites. PMID: 31360695 [PubMed - in process]
Source: Canadian Journal of Gastroenterology - Category: Gastroenterology Tags: Can J Gastroenterol Hepatol Source Type: research
DiscussionIt is important to recognize TC as a potential complication following liver transplantation so as to detect cases earlier in the disease course and begin early goal-directed care.
Source: Clinics and Research in Hepatology and Gastroenterology - Category: Gastroenterology Source Type: research
Liver transplantation (LT) continues to be the gold standard for treating end-stage liver disease, and challenges that are posed to the anesthesiologist during transplantation are well known. Successful liver transplantation requires knowledge, recognition, and treatment of hemodynamic and metabolic disturbances by the anesthesiologist. End-stage liver disease causes unique derangements to the clotting cascade, increasing risk both for hemorrhagic and thrombotic events. Cirrhotic cardiomyopathy may be masked for years because of low systemic vascular resistance in cirrhosis, and overt heart failure can be precipitated by LT.
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Review Article Source Type: research
AbstractCardiogenic liver disease is a common yet poorly characterized complication of advanced heart failure (HF), and may impact clinical management in the setting of heart transplant evaluation. In this retrospective study, we describe clinical and histopathological features of liver injury in advanced HF, with a focus on the role of liver biopsy. Included were 45 HF patients, assessed for possible heart transplant, who underwent liver biopsy for suspected liver disease. Median duration of HF symptoms was 5  years. Most patients had stiff hepatomegaly and elevated bilirubin. Viral hepatitis (19 patients, 42.2%) was...
Source: Internal and Emergency Medicine - Category: Emergency Medicine Source Type: research
Publication date: Available online 8 January 2019Source: Clinics and Research in Hepatology and GastroenterologyAuthor(s): Pascal Lebray, Shaida VarnousSummaryVarious types of liver impairment have been described in patients with end-stage heart failure who are awaiting heart transplantation. The liver impairment may be severe, characterized by a high model for end-stage liver disease (MELD) Score and/or the presence of ascites, both of which are associated with a high risk of failure after single heart transplantation. A liver function assessment is therefore necessary before registration on the heart transplant list, mor...
Source: Clinics and Research in Hepatology and Gastroenterology - Category: Gastroenterology Source Type: research
Publication date: Available online 12 December 2018Source: JACC: Heart FailureAuthor(s): Andrew Xanthopoulos, Randall C. Starling, Takeshi Kitai, Filippos TriposkiadisAbstractHeart failure (HF) and liver disease often co-exist. This is because systemic disorders and diseases affect both organs (alcohol abuse, drugs, inflammation, autoimmunity, infections) and because of complex cardiohepatic interactions. The latter, which are the focus of this review, include the development of acute cardiogenic liver injury and congestive hepatopathy in HF as well as cardiac dysfunction and failure in the setting of liver cirrhosis, nona...
Source: JACC: Heart Failure - Category: Cardiology Source Type: research
When it comes to your beverage of choice, alcoholic beverages are unique. For millions, they are a regular part of the dining experience. They’re often an important component of social events, celebrations, and milestones; we toast people, events, and memories with alcohol. They play a key role in many religious traditions. And, of course, the alcoholic beverage industry is a major economic force, responsible for more than $220 billion in sales annually in the US. And all of this is true despite the well-known and well-publicized risks of drinking too much alcohol. The negative effects of alcohol It should be a surpr...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Alcohol Health Source Type: blogs
Authors: Golfeyz S, Lewis S, Weisberg IS Abstract INTRODUCTION: Hereditary hemochromatosis (HH) is an autosomal recessive disorder that occurs in approximately 1 in 200-250 individuals. Mutations in the HFE gene leads to excess iron absorption. Excess iron in the form of non-transferrin bound iron (NTBI) causes injury and is readily up-taken by cardiomyocytes, pancreatic islet cells and hepatocytes. Symptoms greatly vary among patients and include fatigue, abdominal pain, arthralgias, impotence, decreased libido, diabetes and heart failure. Untreated hemochromatosis can lead to chronic liver disease, fibrosis, cirr...
Source: Expert Review of Gastroenterology and Hepatology - Category: Gastroenterology Tags: Expert Rev Gastroenterol Hepatol Source Type: research
More News: Cardiology | Cirrhosis | CT Scan | Heart | Heart Failure | Heart Transplant | Liver | Liver Disease | Liver Transplant | Lung Transplant | PET Scan | Study | Transplant Surgery | Transplants | Ultrasound | Urology & Nephrology