Single Cell RNA Sequencing of Human Pulmonary Endarterectomy Specimen Reveals Distinct Cell Populations and Gene Profiles

Chronic thromboembolic pulmonary hypertension (CTEPH), is a progressive condition characterized by persistent elevation in pulmonary artery pressure due to thromboembolic occlusion of the pulmonary arteries. Little is known about the cells that make up the cast of pulmonary endarterectomy (PEA) and its immune microenvironment. Here we report a map of the cellular landscape of the human PEA specimen using single-cell RNA sequencing.

Source: The Journal of Heart and Lung Transplantation - March 31, 2020 Category: Transplant Surgery Authors: Y.D. Zhao, S. Wanggou, M. Ding, X.Y. Dong, G. Zhao, Y. Diao, Y. Yao, L. Wu, J. Granton, M. de Perrot Tags: (53) Source Type: research