Lung and Heart-Lung Transplantation for Children with PAH: Dramatic Benefits from the Implementation of High Priority Allocation Program in France
Pulmonary arterial hypertension (PAH) is rare but remains a fatal disease in infants and children despite the recent introduction of targeted therapies. Lung transplantation (LT), first performed in pediatric patients in the 1980s, is the only potentially life-extending option in patients with end-stage PAH but is possible only in tightly selected patients. Size-matching challenges severely restrict the donor organ pool which, in addition to peculiarities of PAH in infants, results in high mortality while on the waiting list.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: J. Le Pavec, S. Feuillet, O. Mercier, P. Prad ère, A. Crutu, V. Florea, L. Savale, D. Bonnet, D. Fabre, S. Mussot, S. Hascoet, M. Humbert, E. Fadel Tags: (145) Source Type: research
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