The Effects of Selenium-Enriched Probiotics on Growth Performance, Oocysts Shedding, Intestinal Cecal Lesion Scores, Antioxidant Capacity, and mRNA Gene Expression in Chickens Infected with Eimeria tenella.

This study was carried out to investigate the effects of selenium-enriched probiotics (SP) supplementation on growth performance, oocysts shedding, intestinal lesions and antioxidant capacities, and mRNA gene expression of local Chinese yellow male chickens infected with Eimeria tenella. One-day-old 270 chickens were randomly assigned into five groups, each consisting of three replicates with 18 chickens per replicate. Chickens in the negative and positive controls (NC, PC, respectively) received basal diets only (0.11 mg Se/kg), whereas the other groups were supplied basal diets with probiotics and designated as (P, 0.11 mg Se/kg), sodium selenite (SS, 0.41 mg Se/kg), and (SP, 0.41 mg Se/kg) groups. At 21 days of age, except the NC group, all other groups were infected by oral gavage with 1.5 × 104 sporulated E. tenella oocysts per chicken. Three chickens were randomly selected from each group for serum, liver, and cecal specimen collection. The results showed that P, SS, and SP had significant increase weight gain and feed intake. Additionally, these groups showed higher activities of serum superoxide dismutase (SOD) and glutathione peroxidase-1 (GPx1) compared to the PC group, whereas feed conversion ratio (FCR), serum catalase (CAT) activity, and malondialdehyde (MDA) content remained lower. Moreover, P, SS, and SP groups had lower oocyst shedding and cecal lesion scores. Significant upregulation of the glutathione peroxidase-1 (GPx1), glutathione peroxidase...
Source: Biological Trace Element Research - Category: Biology Authors: Tags: Biol Trace Elem Res Source Type: research