Caris Life Sciences Launches MI FOLFOXai, Improving Overall Survival by 50% for Metastatic Colorectal Cancer Patients
First AI-powered FOLFOX predictor to guide first-line metastatic colorectal cancer treatment IRVING, Texas, March 31, 2020 -- (Healthcare Sales &Marketing Network) -- Caris Life Sciences®, a leading innovator in molecular science focused on fulfil... Diagnostics, Oncology, Product Launch Caris Life Sciences, MI FOLFOXai, FOLFOX, precision medicine
Recent interest in the role of microbiota in health and disease has implicated gut microbiota dysbiosis in psychiatric disorders including major depressive disorder. Several antidepressant drugs that belong to the class of selective serotonin reuptake inhibitors have been found to display antimicrobial activities. In fact, one of the first antidepressants discovered serendipitously in the 1950s, the monoamine-oxidase inhibitor Iproniazid, was a drug used for the treatment of tuberculosis. In the current study we chronically treated DBA/2J mice for 2 weeks with paroxetine, a selective serotonin reuptake inhibitor, and colle...
Conclusion3D CT angiograms are useful for preoperative evaluation. Accessory middle colic arteries exist and were observed in 14.9% of cases.
Publication date: Available online 2 June 2020Source: Pathology - Research and PracticeAuthor(s): Hyeongjoo Kim, Taewan Kim, Gunn Jaygal, Jongsoo Woo, Chang-Jin Kim, Moo-Jun Baek, Dongjun Jeong
Conclusions: In the largest study to date of symptomatic individuals under 50 years of age undergoing colonoscopy in the USA, advanced CRN was most often detected in the distal colon and was associated with anemia, but not with abnormal bowel habits or abdominal pain. We also found that patients with CRN under 50 years of age were more likely to be male, smokers, and obese. These findings should prompt further investigation of these risk factors alone and in combination.
Young adults are often not aware they can get colon cancer, and doctors are often late to diagnose it in younger patients, according to new research presented at the American Society of Clinical Oncology annual meeting.
Publication date: August 2020Source: Biomedicine &Pharmacotherapy, Volume 128Author(s): Yu-Chang Liu, Jai-Jen Tsai, Yueh-Shan Weng, Fei-Ting Hsu
ConclusionPeople with cancer residing outside major cities had lower survival from some cancers, which is partly due to the greater socio-economic disadvantage of rural residents.
ConclusionOur results suggest thatBRAF-mutant and CIMP-high serrated polyps are not associated with subsequent advanced colorectal neoplasia. Among SSA/Ps,MLH1 methylation may be an important marker to identify high-risk CRC precursors.
Publication date: Available online 2 June 2020Source: Clinica Chimica ActaAuthor(s): Lei Liu, Qiao He, Yan Li, Bing Zhang, Xiaobin Sun, Jing Shan, Biran Pan, Tongtong Zhang, Zihao Zhao, Xiaoyu Song, Yuanbiao Guo
Conclusions: These findings suggest that there may be organ system connections for cancers of the endocrine and digestive systems; etiologic approaches focused on clusters of cancers rather than individual cancers may prove fruitful.