The Therapeutic Effect of Artemisinin and Its Derivatives in Kidney Disease

Artemisinin (ARS) and its derivatives (ARSs) are recommended as the first-line antimalarial drugs for the treatment of malaria. Besides antimalarial function, its potent anti-inflammatory and immunoregulatory properties, as well as the ability to regulate oxidative stress have brought them to a prominent position. As researchers around the world are continually exploring the unknown biological activities of ARS derivatives, experimental studies have shown much progress in renal therapy. This review aims to give a brief overview of the current research on ARSs applications for kidney treatment with the evaluation of therapeutic properties and potential molecular mechanisms.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research

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This study used nationally representative data from demographic and health surveys (DHS) in Namibia, Kenya and Sierra Leone. A direct sisterhood method was used to estimate pregnancy-related deaths based on 7 years of recollection. Findings of the study reveal that death during the antenatal period was the commonest time of death in mothers aged 15-19, while death during delivery and two months after delivery were the leading causes of death for mothers aged 20-24. Pregnancy-related deaths were more prevalent among women with no schooling or primary education than their counterparts with secondary and higher education.Impa...
Source: Journal of Obstetrics and Gynaecology - Category: OBGYN Tags: J Obstet Gynaecol Source Type: research
Leaders of a large study in the United Kingdom that is rigorously testing the malaria drug hydroxychloroquine and other medicines for hospitalized COVID-19 patients say they will stop putting people on the drug because it’s clear it isn’t helping
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news
ARTESUNATE is a drug used for initial treatment of severe malaria in children and adults. Treatment of severe malaria with artesunate should always be followed by a complete treatment course of an appropriate antimalarial drug.
Source: FDA Center for Drug Evaluation and Research - What's New - Category: Drugs & Pharmacology Authors: Source Type: news
A group of conservative US doctors has sued the Food and Drug Administration for limiting use of the malaria drug hydroxychloroquine for COVID-19, arguing that the therapy should be made widely available to fight the pandemic.Reuters Health Information
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Medscape Today News Source Type: news
This study analyzes the influence of socio-environmental health determinants on the maintenance of Plasmodium vivax malaria at the borders between French Guiana and Brazil. This study was carried out between 2011 and 2015 in the city of Oiapoque, Amap á, situated in the Brazilian Amazon region. The sample included 253 individuals of both sexes aged between 10 and 60 years. The disease was predominant in 63.64% (161/253) adult males. The most affected age group was 20 to 29 years old, with 30% (76/253). About 84.6% did not complete high school, w hile 29.6% (75/253) of the cases had not finished the first degree. Con...
Source: Saude e Sociedade - Category: International Medicine & Public Health Source Type: research
Condition:   Malaria Intervention:   Other: IR3535 (3-(N-acetyl-N-butyl) aminopropionic acid ethyl ester) house spraying Sponsors:   Universidade Nova de Lisboa;   Centro de Investigação Operacional da Beira, Mozambique;   Fundação Belmiro de Azevedo, Portugal Not yet recruiting
Source: - Category: Research Source Type: clinical trials
Hydroxychloroquine has become controversial but it is not a treatment for Covid, say Oxford researchers.
Source: BBC News | Health | UK Edition - Category: Consumer Health News Source Type: news
British scientists halted a large trial on Friday that had been exploring the use of the anti-malaria drug hydroxychloroquine in patients with the pandemic disease COVID-19 after initial results showed no evidence of benefit.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
An influential study that found hydroxychloroquine increased the risk of death in COVID-19 patients has been withdrawn a week after it led to major trials being halted, adding to confusion about a malaria drug championed by U.S. President Donald Trump.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
(Natural News) One of the most vocal media opponents to hydroxychloroquine, the generic anti-malaria drug that President Trump touted as having benefits, is NBC News. For the past several weeks at least, NBC News has been churning out story after story claiming that hydroxychloroquine does not help prevent or treat the Wuhan coronavirus (COVID-19). In...
Source: - Category: Consumer Health News Source Type: news
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