Remembering the “Forgotten Valve”: Further Insight Into Transcatheter Tricuspid Valve Repair for Right Heart Failure∗

Publication date: April 2020Source: JACC: Heart Failure, Volume 8, Issue 4Author(s): Wayne Batchelor, JoAnn Lindenfeld
Source: JACC: Heart Failure - Category: Cardiology Source Type: research

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Authors: Poulin A, Beaupré F, Gravel C, Hadjadj S, Bernier M, Beaudoin J, O'Connor K, Ferreira-Neto AN, Wintzer J, Dumont E, Dagenais F, Rodés-Cabau J, Paradis JM Abstract BACKGROUND: Many patients referred for a MitraClip intervention are finally refused for this intervention, and data are very scarce on their outcomes. Our study sought to determine the characteristics and outcomes of patients who are referred to a mitral valve clinic and are finally denied from a percutaneous mitral edge-to-edge repair. METHODS: A total of 210 patients referred to our clinic for severe mitral regurgitation were ...
Source: The Journal of Invasive Cardiology - Category: Cardiology Tags: J Invasive Cardiol Source Type: research
European Journal of Heart Failure, EarlyView.
Source: European Journal of Heart Failure - Category: Cardiology Authors: Tags: Editorial Comment Source Type: research
European Journal of Heart Failure, EarlyView.
Source: European Journal of Heart Failure - Category: Cardiology Authors: Tags: Editorial Comment Source Type: research
AbstractAimsThe aim of this study was to compare the outcomes of surgical mitral valve repair or replacement (sMVR) and percutaneous edge ‐to‐edge repair using MitraClip (pMVR) in patients with severe left ventricular dysfunction affected by functional mitral regurgitation (FMR).Methods and resultsWe retrospectively identified 132 patients with left ventricular ejection fraction (LVEF)  ≦ 30% submitted to sMVR (n = 47) or pMVR (n = 85) for FMR at our centre from January 2013 to December 2017. To adjust for baseline imbalances, we used a propensity score matching by age, logistic EuroSCOR...
Source: ESC Heart Failure - Category: Cardiology Authors: Tags: Original Research Article Source Type: research
AbstractAimsThe purpose of this study is to identify echocardiography predictors of clinical response and reverse left ventricular (LV) remodelling in patients with functional mitral regurgitation (FMR) treated with MitraClip.Method and resultsWe retrospectively analysed 86 high surgical risk patients with severe FMR; of those, 58 were implanted a MitraClip, and 28 received medical treatment and served as controls. At baseline and at 1 ‐year follow‐up, we performed clinical and echocardiography evaluation to assess global longitudinal strain (GLS) and myocardial work [global work index (GWI), global constructive work (...
Source: ESC Heart Failure - Category: Cardiology Authors: Tags: Original Research Article Source Type: research
ConclusionsGuideline ‐directed medical therapy is frequently underdosed in HFrEF patients with SMR undergoing pMVR. Downtitration of medications after procedure is associated with poor prognosis.
Source: ESC Heart Failure - Category: Cardiology Authors: Tags: Original Research Article Source Type: research
This study aimed to quantify the morphologic, hemodynamic and structural changes, and evaluate the biomechanical interaction between the MitraClip and the left heart (LH) complex of a heart failure patient with functional MR using a fluid-structure interaction (FSI) modeling framework. MitraClip implantation using lateral, central and double clip positions, as well as combined annuloplasty procedures were simulated in a patient-specific LH model that integrates detailed anatomic structures, incorporates age- and gender-matched non-linear elastic material properties, and accounts for mitral chordae tethering. Our results sh...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Tetrallogy of Fallot (TOF) is the most frequent form of cyanotic congenital heart disease. Despite advances in surgical and medical treatment, mortality remains high. Residual dysfunction of the pulmonary valve (PV) after correction of right ventricular outflow tract obstruction is an important cause of morbidity, leading to irreversible right ventricular dysfunction, arrhythmias, heart failure and occasionally, death. The strategies for PVR have evolved over the last decades, and the timing of the intervention remains the foundation of the decision-making process. Symptoms of heart failure are unreliable indicators for op...
Source: Journal of Thoracic Imaging - Category: Radiology Tags: Review Articles Source Type: research
Mitral valve disease is the one of the most frequent causes for heart failure and associated with poor prognosis and mortality. Surgical replacement or repair is still gold standard therapy despite the development of catheter-based techniques and different types of surgical approaches are being evolved [1]. Numerous minimally invasive techniques to lessen the invasiveness and have been gaining popularity in the last decades, moreover, the results are promising comparing to standard approaches. [2] In the last 20  years, many different minimal invasive methods have been described including partial sternotomy, parasternal ...
Source: International Journal of Cardiology - Category: Cardiology Authors: Tags: Editorial Source Type: research
CONCLUSIONS: Echocardiographic parameters, including the EROA/LVEDV ratio, have not independent prognostic value in patients undergoing MitraClip. High surgical risk, advanced symptoms and non-optimal MR reduction increase the relative risk of 2-year clinical events. PMID: 32287037 [PubMed - as supplied by publisher]
Source: EuroIntervention - Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research
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