A pilot study of the sequencing of the intestinal microbiota for colon cancer

In this study, they compare two sequencing methods and design a bioinformatic analysis to establish the basis of a wide study in the research of early detection markers of colon cancer.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news

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ConclusionIt needs attention that antibiotics use is associated with a higher risk of CRC, especially for colon cancer. Clinicians should be aware of the potential risk of CRC when prescribing anti-anaerobic antibiotics, penicillins, and quinolones in the future. Further studies are needed to assess any potential differences by tumor sites and class of antibiotics.
Source: International Journal of Colorectal Disease - Category: Gastroenterology Source Type: research
Authors: Martínez Ortega P, Cienfuegos JA, Baixauli J, Sánchez Justicia C, Abengózar M, Pastor Idoate C, Hernández Lizoáin JL Abstract BACKGROUND: the prognostic value of the number of lymph nodes isolated (
Source: Revista Espanola de Enfermedades Digestivas - Category: Gastroenterology Tags: Rev Esp Enferm Dig Source Type: research
Journal of Agricultural and Food ChemistryDOI: 10.1021/acs.jafc.0c02604
Source: Journal of Agricultural and Food Chemistry - Category: Food Science Authors: Source Type: research
CONCLUSION: A certain amount of capsaicin has a protective effect against colon adenocarcinoma and the dose concentrations are important for the most reliable treatment. PMID: 32490651 [PubMed - as supplied by publisher]
Source: Turkish Journal of Medical Sciences - Category: General Medicine Tags: Turk J Med Sci Source Type: research
AbstractPurposeVolume-outcome relationship is well established in elective colorectal surgery for cancer, but little is known for patients managed for obstructive colon cancer (OCC). We aimed to compare the management and outcomes according to the hospital volume in this particular setting.MethodsPatients managed for OCC between 2005 and 2015 in centers of the French National Surgical Association were retrospectively analyzed. Hospital volume was dichotomized between low and high volume on the median number of patients included per center during the study period.ResultsA total of 1957 patients with OCC were managed in 56 c...
Source: International Journal of Colorectal Disease - Category: Gastroenterology Source Type: research
Conditions:   Stage II Colon Cancer;   Stage III Colon Cancer Intervention:   Sponsor:   Boryung Pharmaceutical Co., Ltd Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Metastatic Colon Cancer;   Surgery Interventions:   Procedure: resection of primary tumor;   Drug: XELOX;   Drug: mFOLFOX6 Sponsor:   Fudan University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Stage II Colon Cancer;   Stage III Colon Cancer Intervention:   Sponsor:   Boryung Pharmaceutical Co., Ltd Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Metastatic Colon Cancer;   Surgery Interventions:   Procedure: resection of primary tumor;   Drug: XELOX;   Drug: mFOLFOX6 Sponsor:   Fudan University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
This study was designated to explore the role of cancer stem cells (CSCs) during chemically induced mouse colon carcinogenesis (by 1,2- dimethylhydrazine dihydrochloride, DMH) with/or without the treatment with a targeted (anti-COX-2) therapeutic drug, celecoxib. Two experiments were conducted. The first, a short-term, 16-week mouse colon carcinogenesis bioassay, demonstrates the early stages of colon carcinogenesis. The other is a medium-term, 32-week mouse colon cancer experiment that mimics an end point of colon malignancy. Colon tumors were detected in animals after 32 weeks; histopathologically, they varied from benig...
Source: Journal of Environmental Pathology, Toxicology and Oncology - Category: Environmental Health Tags: J Environ Pathol Toxicol Oncol Source Type: research
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