Breakthrough pain is not a fixed fraction of constant cancer pain

AbstractThis journal recently published a paper by Currow et al., entitled "A randomised, double ‐blind, crossover, dose ranging study to determine the optimal dose of oral opioid to treat breakthrough pain for patients with advanced cancer already established on regular opioids” (Currow et al., 2010). Currow et al. demonstrated that for breakthrough pain (BTP) there were no differences bet ween giving rescue opioids doses of 1/6, 1/8 or 1/12 of the scheduled daily opioid dose.

Source: European Journal of Pain - March 31, 2020 Category: Anesthesiology Authors: P ål Klepstad, Morten Thronæs, Erik Torbjørn Løhre Tags: COMMENTARY Source Type: research