Increased brain vitamin D receptor expression and decreased expression of cathelicidin antimicrobial peptide in individuals who died by suicide - Postolache TT, Akram F, Lee EE, Lowry CA, Stiller JW, Brenner LA, Streeten EA, Turecki G, Dwivedi Y.

Vitamin D deficiency is associated with immune dysregulation, increased vulnerability to infections, depression, and suicidal behavior. One mediator of vitamin D-dependent immune regulation and antimicrobial defense is the cathelicidin antimicrobial peptid...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

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Feeling depressed for no reason? Here’s what you should know. Depression can become a huge problem in your life, but many people may not actually recognize the signs of depression or symptoms; instead, they’ll just assume that they’re sad. But if you’re waking up depressed, or feeling depressed for no reason every day, then you may not just be sad or going through a “phase.”  9 Subtle Signs Of Depression I Was Too Depressed To Notice Wondering “Why am I depressed?” all the time might make you feel like you’re going crazy or that you’ll never feel b...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Depression Disorders General LifeHelper Mental Health and Wellness Psychiatry Publishers Self-Help YourTango Emptiness Hopelessness Sad Sadness Seasonal Affective Disorder Suicidal Thoughts Thyroid Source Type: blogs
In trying to cope with the debilitating symptoms of depression, people often turn to vitamins, supplements, herbs, or home remedies first. And it’s no wonder — such efforts to alleviate symptoms are often far less expensive and easier to obtain. For some, it may be a part of their rationalization that their depression “isn’t all that bad,” if it can be treated with vitamins and supplements. Many people find relief in taking vitamins and supplements for depression. It is also one of the most well-researched topics, so we know what the science has to say about the efficacy of such treatments. Bu...
Source: Psych Central - Category: Psychiatry Authors: Tags: Depression Diet & Nutrition General Medications Miscellaneous Drugs supplements for depression vitamins for depression Source Type: news
CASE: Alex is a 14-year-old Portuguese-American boy with a psychiatric history starting at age 5 who presents to your primary care practice after an insurance change. He was delivered prematurely at 32 weeks and diagnosed with congenital hypothyroidism at the age of 6 weeks and growth hormone deficiency at the age of 2 years; he is in active treatment for both. He otherwise met developmental milestones on time yet continues to have significant fatigue despite adequate sleep and vitamin D supplementation. His family history is remarkable for maternal anxiety, depression, suicidal thoughts, and previous attempted suicide...
Source: Journal of Developmental and Behavioral Pediatrics - Category: Child Development Tags: Challenging Case Source Type: research
In conclusion, long-term aerobic exercise appears to attenuate the decline in endothelial vascular function, a benefit which is maintained during chronological aging. However, currently there is not enough evidence to suggest that exercise interventions improve vascular function in previously sedentary healthy older adults. Hijacking the Proteasome to Dispose of Unwanted Molecules in Age-Related Disease https://www.fightaging.org/archives/2019/03/hijacking-the-proteasome-to-dispose-of-unwanted-molecules-in-age-related-disease/ Cells are equipped with a protein disposal system in the form of the proteaso...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Conclusion: When a patient presents with a history of psoriasis, the dental practitioner should expand the medical history process to ascertain possible correlated diseases. Information gleaned from this interview process may prompt the attending dental clinician to seek consultation with the patient's physician to gain greater insight to the severity of any prevailing comorbidities and engage in discussions for possible modifications in dental management. Knowledge of psoriatic comorbidities and their possible impact on dental care may improve clinical outcomes.
Source: Quintessence International - Category: Dentistry Source Type: research
Suicidal erythrocyte death or eryptosis contributes to or even accounts for anemia in a wide variety of clinical conditions, such as iron deficiency, dehydration, hyperphosphatemia, vitamin D excess, chronic kidney disease (CKD), hemolytic-uremic syndrome, diabetes, hepatic failure, malignancy, arteriitis, sepsis, fever, malaria, sickle-cell disease, beta-thalassemia, Hb-C and G6PD-deficiency, Wilsons disease, as well as advanced age. Moreover, eryptosis is triggered by a myriad of xenobiotics and endogenous substances including cytotoxic drugs and uremic toxins. Eryptosis is characterized by cell membrane scrambling with ...
Source: Cellular Physiology and Biochemistry - Category: Cytology Source Type: research
It happens every year. As I watch the first golden leaves fall from the oak tree outside our house and listen to the sound of the cicadas ushering in autumn, my anxiety spikes. I used to think I was relapsing into depression, but having been through this year after year (and documenting it in my mood journal), I now know I’m just going through my annual bout of autumn anxiety: a nervous feeling in my gut that begins the last week of August and continues through the first weeks of September. I’m hardly alone. Many of my friends who battle anxiety — and even those that don’t have a mood...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Alternative and Nutritional Supplements Anxiety and Panic Bipolar Depression Inspiration & Hope Mental Health and Wellness Personal Self-Help Stress Allergies autumn anxiety Breathing Technique cytokines Exhaustion fall fever Source Type: blogs
Dear Colleagues: Welcome to the May–June 2016 issue of Innovations in Clinical Neuroscience. I am pleased to start the issue with the first of a series of articles we’ll be publishing that will explore the emerging field of digital medicine and how innovative technology can improve patient outcomes in the field of neuroscience. I am honored to coauthor the series with Drs. Arshya Vahabzadeh and Ned Sahin from BrainPower, a company that develops brain science-driven software for wearables (e.g., Google Glass™) into neuro-assistive devices for the educational challenges of autism. In our first installment, ...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Current Issue Drug Development Editor's Message: Issue Highlights Neurology Psychiatry Amir H. Kalali Innovations in Clinical Neuroscience Source Type: research
Dear Colleagues: Welcome to the May–June 2016 issue of Innovations in Clinical Neuroscience. I am pleased to start the issue with the first of a series of articles we’ll be publishing that will explore the emerging field of digital medicine and how innovative technology can improve patient outcomes in the field of neuroscience. I am honored to coauthor the series with Drs. Arshya Vahabzadeh and Ned Sahin from BrainPower, a company that develops brain science-driven software for wearables (e.g., Google Glass™) into neuro-assistive devices for the educational challenges of autism. In our first installment, ...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Current Issue Drug Development Editor's Message: Issue Highlights Neurology Psychiatry Amir H. Kalali Innovations in Clinical Neuroscience Source Type: research
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