Mapping cannabis potency in medical and recreational programs in the United States - Cash MC, Cunnane K, Fan C, Romero-Sandoval EA.

Cannabis related online searches are associated with positive attitudes toward medical cannabis, particularly when information is obtained from dispensaries. Since pain is the main reason for medicinal cannabis use, information from dispensary websites has...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

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Conclusion: Recurrent pancreatitis is suggested as the etiology of atypical HUS in this patient and this condition should be recognized and treated in a timely manner for optimal clinical outcomes.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
ConclusionSymptoms of polyneuropathy following adjuvant docetaxel and oxaliplatin persist 5  years after treatment and affect quality of life negatively.
Source: Cancer Medicine - Category: Cancer & Oncology Authors: Tags: ORIGINAL RESEARCH Source Type: research
NEW BRUNSWICK, NJ, May 27, 2020 — The Janssen Pharmaceutical Companies of Johnson &Johnson today announced that the U.S. Food and Drug Administration (FDA) has granted approval for a new pediatric formulation of SIRTURO® (bedaquiline). SIRTURO® is now indicated for use as part of combination therapy in the treatment of adult and pediatric patients (5 years and older and weighing at least 15 kg) with pulmonary multidrug-resistant tuberculosis (MDR‑TB). In the U.S., the medicine should be reserved for use when an effective treatment regimen cannot otherwise be provided. This indication received accelera...
Source: Johnson and Johnson - Category: Pharmaceuticals Tags: Innovation Source Type: news
“Since we’ve been in quarantine,” announces Susan, a binge eating client, “I can’t stop overeating. Now that I’m in lockdown, I wish I had lockjaw!” Danny laughingly echoes the same feeling: “Now that I can’t go to work, I’m involved instead in many diverse activities at home throughout the day — there’s snacking, grazing, munching, nibbling, noshing, chowing down, and sometimes even eating meals!” Susan and Danny have it right — emotional eating struggles during this time of COVID-19 are alive and well. In truth, worry, anxiety, fear, grie...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Binge Eating Eating Disorders Binge Eating Disorder Compassion coronavirus COVID-19 Emotional Eating Mindfulness pandemic social distancing Source Type: blogs
[Abstract unavailable] Language: en...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Abstract Substance use disorders (SUDs) are frequently accompanied by affective symptoms that promote negative reinforcement mechanisms contributing to SUD maintenance or progression. Despite their widespread use as analgesics, chronic or excessive exposure to alcohol, opioids, and nicotine produces heightened nociceptive sensitivity, termed hyperalgesia. This review focuses on the contributions of neuropeptide (CRF, melanocortin, opioid peptide) and cytokine (IL-1β, TNF-α, chemokine) systems in the development and maintenance of substance-induced hyperalgesia. Few effective therapies exist for either c...
Source: Neuropharmacology - Category: Drugs & Pharmacology Authors: Tags: Neuropharmacology Source Type: research
CONCLUSIONS: The findings indicate that the Polish adaptation of the SBQ-R by Osman et al. has good psychometric characteristics and can be considered in both research and clinical practice. PMID: 32447359 [PubMed - as supplied by publisher]
Source: Psychiatria Polska - Category: Psychiatry Tags: Psychiatr Pol Source Type: research
Conclusions: Ketamine has suggested potential benefit in several disease states impacting critically ill patients including pain, alcohol withdrawal syndrome, status epilepticus, and acute agitation. Further supporting evidence is needed to validate its use in the setting of critical illness.
Source: Critical Care Medicine - Category: Emergency Medicine Tags: Concise Definitive Review Source Type: research
This review identified prospective cohort studies in the general population, which showed incidence (23 papers) and risk factors (37 papers) for fibromyalgia and chronic widespread pain. Median incidence of physician diagnosed fibromyalgia in the general population was 4.3 per 1000 person-years (range = 0.33-18.8) but 14.0 (1.2-32.7) if medical illness was present. Median incidence of chronic widespread pain was 12.5 per 1000 person-years (7.2-81.6) but 67 per 1000 person years (14.8-124) for those with pre-existing pain. Risk factors included various childhood difficulties, female sex (except with pre-existing medical dis...
Source: Pain - Category: Anesthesiology Tags: Comprehensive Review Source Type: research
Pathologic alcohol use affects more than 2 billion people and accounts for nearly 6% of all deaths worldwide. There are three medications approved for the treatment of alcohol use disorder by the US Food and Drug Administration (FDA): disulfiram, naltrexone (oral and long-acting injectable), and acamprosate. Of growing interest is the use of anticonvulsants for the treatment of alcohol use disorder, although currently none are FDA approved for this indication. Baclofen, a γ-aminobutyric acid B receptor agonist used for spasticity and pain, received temporary approval for alcohol use disorder in France.
Source: Mayo Clinic Proceedings - Category: Internal Medicine Authors: Tags: Review Source Type: research
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