Activation of autophagy inhibits nucleotide ‐binding oligomerization domain‐like receptor protein 3 inflammasome activation and attenuates myocardial ischemia‐reperfusion injury in diabetic rats

ConclusionActivation of autophagy can suppress the formation of NLRP3 inflammasome, which in turn attenuates myocardial ischemia ‐reperfusion injury in diabetic rats.

Source: Journal of Diabetes Investigation - March 31, 2020 Category: Endocrinology Authors: Dengwen Zhang, Yi He, Xiaodong Ye, Yin Cai, Jindong Xu, Liangqing Zhang, Mingyi Li, Hao Liu, Sheng Wang, Zhengyuan Xia Tags: Original Article Source Type: research