Methotrexate Discontinuation and Dose Decreases After Therapy With Tocilizumab: Results From the Corrona Rheumatoid Arthritis Registry

ConclusionsA considerable proportion of patients initiating TCZ discontinued or decreased their MTX dose after TCZ initiation. Improvements in disease activity and functionality were observed in patients who decreased or stopped MTX. This real-world study confirmed prior observations that discontinuing or decreasing MTX may be a treatment strategy for patients initiating TCZ combination therapy.Trial RegistrationClinicalTrials.gov identifier, NCT01402661.

http://link.springer.com/10.1007/s40744-020-00200-z

Source: Rheumatology and Therapy - March 29, 2020 Category: Rheumatology Source Type: research