Spiky follicular mycosis fungoides and hidradenitis suppurativa-like lesions in a patient - complete remission with interferon alpha,
Abstract White fibrous papulosis of the neck is a rare entity, with fewer than 50 cases described. It is a benign pathology whose main interest lies in its broad differential diagnosis, especially with pseudoxanthoma elasticum. The authors report the case of a 77-year-old woman with multiple yellow-white monomorphic papules on the posterior cervical region, with years of evolution. Cutaneous biopsy revealed a nodular area in the superficial and middle reticular dermis, with slight thickening of the collagen fibers and focally enlarged elastic fibers, aspects highlighted in the Verhoeff staining that additionally showed absence of elastic fibers in the papillary dermis.
CONCLUSION: Pityriasis lichenoides chronica should be included among the broad clinical spectrum of chronic inflammatory skin diseases which may occur during treatment with TNF-alpha antagonists. J Drugs Dermatol. 2020;19(5): doi:10.36849/JDD.2020.2191. PMID: 32484616 [PubMed - as supplied by publisher]
We present a patient with an initially suspected diagnosis of benign interface dermatitis with a differential diagnosis of mycosis fungoides that was later found to be an aggressive extranodal natural killer/T-cell lymphoma of a nasal type and with a dismal prognosis. PMID: 32483814 [PubMed - as supplied by publisher]
shalko M, Mitteldorf C, Akilov O, Ortiz-Romero P, Estrach T, Vakeva L, Enz PA, Wobser M, Bayne M, Jonak C, Rubeta M, Forbes A, Bates A, Battistella M, Amel-Kashipaz R, Vydianath B, Combalia A, Georgiou E, Hauben E, Hong EK, Jost M, Knobler R, Amitay-Laish I, Miyashiro D, Cury-Martins J, Martinez X, Muniesa C, Prag-Naveh H, Nikolaou V, Quint K, Ram-Wolff C, Rieger K, Stranzenbach R, Szepesi Á, Alberti-Violetti S, Felicity E, Cerroni L, Kempf W, Whittaker S, Willemze R, Kim Y, Scarisbrick JJ Abstract BACKGROUND: The PROspective Cutaneous Lymphoma International Prognostic Index (PROCLIPI) Study is a prospectiv...
The 4th Annual Symposium on Hidradenitis Suppurativa (SHSA) took place on 1-3 November 2019 at the Westin Book Cadillac Hotel in Detroit, Michigan, U.S.A. This symposium was a joint meeting of the United States Hidradenitis Suppurativa Foundation (HSF) and the Canadian Hidradenitis Suppurativa Foundation (CHSF). This cross- disciplinary meeting with experts from around the world was an opportunity to discuss the most recent advances in the study of hidradenitis suppurativa (HS) pathogenesis, clinical trials, classification, scoring systems, complementary/ alternative medical treatments (CAM), diet, pain management, surgica...
PMID: 32476130 [PubMed - as supplied by publisher]
Abstract Hidradenitis suppurativa (HS), also known as acne inversa, is a chronic inflammatory disorder of the pilosebaceous units. To date, studies on the risk of keratinocyte carcinoma (KC), defined as basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), among HS patients have been limited. We performed a case-control study comparing the incidence of BCC and SCC in HS patients (cases) to that in acne vulgaris patients (controls), which is also an inflammatory disorder of the pilosebaceous unit. PMID: 32473027 [PubMed - as supplied by publisher]
In their recent publication Assan et al1 have shown that both IgG and IgA anti–Saccharomyces cerevisiae antibodies (ASCAs) are associated with hidradenitis suppurativa (HS).1 As the authors state, ASCA positivity has long been associated with Crohn disease and has recently been identified as a biomarker for spondyloarthritis (SpA). However, both Crohn disease and SpA comprise distinct phenotypes. The phenotype in Crohn disease can change from an inflammatory phenotype, to a fibrostenotic or penetrating phenotype with respectively severe stricturing or fistulation.
We read with interest the correspondence by van Straalen1 about our article reporting an association between anti –Saccharomyces cerevisiae antibodies (ASCAs) and hidradenitis suppurativa (HS), mainly in its severe and inflammatory forms, in comparison with healthy controls and severe psoriasis vulgaris.2
This population-based study examines the prevalence of cancer in patients with hidradenitis suppurativa.