Influence of Cytochrome P450 2D6 Polymorphisms on the Efficacy of Oral Propranolol in Treating Infantile Hemangioma.
Conclusion: The response to propranolol treatment in IH patients was associated with the gene polymorphism of CYP2D6 (rs1135840). A low-dose propranolol regimen was effective and safe in young infants with IH. The change of serum VEGF levels after one month's treatment could not be used to predict the response rate to propranolol.
PMID: 32219146 [PubMed - as supplied by publisher]
Source: Biomed Res - Category: Research Authors: Wang L, Zheng K, Li X, Wang Y, Xu Q Tags: Biomed Res Int Source Type: research