Coronavirus survivors ’ blood plasma could be used to fight infection

Patients, carers and NHS staff could receive experimental antibody treatmentCoronavirus – latest updatesSee all our coronavirus coverageDoctors have drawn up plans to infuse British coronavirus patients and their carers with blood plasma harvested from “hyperimmune” people who have recovered from the infection in an attempt to save lives.The experimental treatment will be directed at patients who are admitted to hospital with pneumonia caused by the virus in the hope that it reduces the number who end up on ventilators in intensive care units (ICUs).Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Medical research Health Infectious diseases Coronavirus outbreak UK news Science Source Type: news

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This article provides a Bayesian methodology to estimate outbreak size from one or more surveillance systems such as virologic testing of pneumonia cases or samples from a network of general practitioners.
Source: Epidemiology - Category: Epidemiology Tags: Infectious diseases Source Type: research
Vidya M Mahalmani, Dhruv Mahendru, Ankita Semwal, Sukhmeet Kaur, Harpinder Kaur, Phulen Sarma, Ajay Prakash, Bikash MedhiIndian Journal of Pharmacology 2020 52(2):117-129 In December 2019, severe acute respiratory syndrome-coronavirus-2, a novel coronavirus, initiated an outbreak of pneumonia from Wuhan in China, which rapidly spread worldwide. The clinical characteristics of the disease range from asymptomatic cases or mild symptoms, which include nonspecific symptoms such as fever, cough, sore throat, headache, and nasal congestion to severe cases such as pneumonia, respiratory failure demanding mechanical ventilation t...
Source: Indian Journal of Pharmacology - Category: Drugs & Pharmacology Authors: Source Type: research
In December 2019, reports of viral pneumonia came out of Wuhan city in Hubei province in China. In early 2020, the causative agent was identified as a novel coronavirus (CoV) sharing some sequence similarity with SARS-CoV that caused the severe acute respiratory syndrome outbreak in 2002. The new virus, named SARS-CoV-2, is highly contagious and spread rapidly across the globe causing a pandemic of what became known as coronavirus infectious disease 2019 (COVID-19). Early observations indicated that cardiovascular disease (CVD) patients are at higher risk of progression to severe respiratory manifestations of COVID-19 incl...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Abstract The novel coronavirus pneumonia (NCP) outbreak occurred in Wuhan, China at the end of 2019. Here, we report the clinical characteristics and therapeutic procedure for a case of severe NCP. The patient was started on glucocorticoids and non-invasive ventilator treatment. After treatment, the patient ’ s symptoms improved, and the status was confirmed as NCP negative. Our results may provide clues for the treatment of NCP.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
WHO is urging countries to investigate any suspicious deaths so virus can be better understoodCoronavirus – latest updatesSee all our coronavirus coverageA day before the first confirmed fatality from coronavirus outside mainland China was reported on 2 February this year, thedeath of the influential guitarist and musician Andy Gill was announced. The 64-year-old, who fronted the post-punk band Gang of Four, died of pneumonia after two weeks in St Thomas ’ hospital in London.The trajectory of Gill ’s illness, which took medics looking after him in January by surprise, is now familiar – sudden deteri...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Coronavirus outbreak Science Infectious diseases Medical research Microbiology World news UK news Source Type: news
In December 2019, an outbreak of new coronavirus pneumonia occurred in Wuhan, Hubei, China1. The rapid increase in confirmed cases and deaths has created problems such as stress, anxiety and depression in the general population2. On March 14th, the Spanish Government declared a state of emergency. In the case of the COVID-19 outbreak, the first waves of epidemiological data show that it disproportionately affects older people (as reported in China) but currently, relatively little is known about its wider impact on mental health3.
Source: The American Journal of Geriatric Psychiatry - Category: Geriatrics Authors: Source Type: research
Conclusion: The current prevention and control measures have effectively reduced the transmissibility of COVID-19; however, R 0t is still larger than the threshold 1. The results show that the government adopting the Wuhan lockdown strategy plays an important role in restricting the potential infected persons in Wuhan outflow from the epidemic area and avoiding a nationwide spread by quickly controlling the potential infection in Wuhan. Meanwhile, since Jan. 18, 2020, the people successively accessed COVID-19-related information via the Internet, which may help to effectively implement the government's prevention and contr...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
We report the case of a 50-year-old man affected by SARS-CoV-2 pneumonia, who developed acute pulmonary embolism.
Source: Journal of Thrombosis and Thrombolysis - Category: Hematology Source Type: research
Days before she tested positive for COVID-19 in early April, Tanya Beckford was already worried about dying because of the conditions in the Connecticut nursing home where she has worked for 23 years. She wasn’t feeling well and says she and her co-workers, facing a shortage of masks, gloves and gowns, had started wearing plastic trash bags over their uniforms for protection as they cared for infected residents. Beckford, a certified nursing assistant (CNA) in the Alzheimer’s unit at Newington Rapid Recovery Rehab Center in Newington, Connecticut, had been running a low-grade fever but says the facility was on...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Source Type: news
Conclusions: The outbreak of the epidemic could promote coronavirus research, meanwhile, coronavirus research contributes to overcoming the epidemic. Attention should be drawn to the latest popular research, including “Spike protein,” “Receptor binding domain,” and “Vaccine.” Therefore, more and more efforts will be put into mechanism research and vaccine research and development, which can be helpful to deal with the epidemic.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research
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