A Practical Approach to Running a Scarce Resource Allocation Team (SRAT)

Jack Iwashyna A Practical Approach to Running a Scarce Resource Allocation Team (SRAT) Practical guidance on how Scarce Resource Allocation Teams (SRATs) should conduct themselves if hospital resources are overwhelmed.
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Intensive Care coronavirus Coronaviruses covid-19 covid19 ethics rationing SARS-CoV-2 Scarce Resource Allocation Teams SRAT Source Type: blogs

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Authors: Liu W, Zhou P, Chen K, Ye Z, Liu F, Li X, He N, Wu Z, Zhang Q, Gong X, Tang Q, Du X, Ying Y, Xu X, Zhang Y, Liu J, Li Y, Shen N, Couban RJ, Ibrahim QI, Guyatt G, Zhai S Abstract BACKGROUND: Antiviral medications are being given empirically to some patients with coronavirus disease 2019 (COVID-19). To support the development of a COVID-19 management guideline, we conducted a systematic review that addressed the benefits and harms of 7 antiviral treatments for COVID-19. METHODS: We searched MEDLINE, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), PubMed and 3 Chinese databases (CNKI, WA...
Source: Canadian Medical Association Journal - Category: General Medicine Tags: CMAJ Source Type: research
Conditions:   COVID;   Sars-CoV2;   SARS-Associated Coronavirus as Cause of Disease Classified Elsewhere Intervention:   Drug: N-acetylcysteine Sponsor:   Cambridge Health Alliance Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Covid-19 is is still a threat to most in Britain. If we allow it to spread now, a deadly second wave in winter could be the resultDr Rupert Beale heads the cell biology of infection laboratory at the Francis Crick Institute in LondonCoronavirus – latest updatesSee all our coronavirus coverageThe lockdown approach to combating Covid-19 has been undeniably effective. The surge in cases was stopped, the NHS was not overwhelmed, and many deaths were prevented. At the Francis Crick Institute, we could see the dramatic effect on cases, as we ’ve been testing for Sars-CoV-2 to support our local hospitals. When we ran ...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Coronavirus outbreak Infectious diseases Science UK news World news Medical research Microbiology Source Type: news
CONCLUSIONS: SARS-Cov-2 has emerged as a worldwide threat, currently affecting 170 countries and territories across the globe. There is still much to be understood regarding SARS-CoV-2 about its virology, epidemiology and clinical management strategies; this knowledge will be essential to both manage the current pandemic and to conceive comprehensive measures to prevent such outbreaks in the future. PMID: 32495923 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Authors: Prajapati S, Sharma M, Kumar A, Gupta P, Narasimha Kumar GV Abstract In the 21st century, human civilization has witnessed three major epidemics caused by Coronaviruses namely severe acute respiratory syndrome coronavirus (SARS CoV) in 2003, Middle East respiratory syndrome coronavirus (MERS CoV) in 2012 and 2019 novel coronavirus (2019 nCoV) or coronavirus disease (COVID 19) in 2019. Among these, COVID-19 has greater transmission and mortality rate. 2019 nCoV belongs to a large family of positive sense single-stranded RNA viruses (+ssRNA) that can be isolated in different animal species. The most communal...
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
CONCLUSIONS: The viral shedding exhibited different patterns during treatment. Immune insufficiency is responsible for the delayed viral clearance, suggesting that an immunomodulator should be considered to promote viral clearance in patients with low lymphocyte counts. PMID: 32495917 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Conclusion: Our study aims to systematically present the clinical evidence of LHQWG in treating COVID-19, which will be of significant meaning for further research and clinical practice. OSF registration number: 10.17605/OSF.IO/27SBU.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research
Conclusion: Clinicians must be aware of the presentation of COVID-19 in children because it differs from that in adults.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
TACB Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection depends on viral polyprotein processing, catalysed by the main proteinase (Mpro). The solution of the SARS-CoV-2 Mpro structure allowed the investigation of potential inhibitors. This work aims to provide first evidences of the applicability of commercially approved drugs to treat coronavirus disease-19 (COVID-19). We screened 4,334 compounds to found potential inhibitors of SARS-CoV-2 replication using an in silico approach. Our results evidenced the potential use of coagulation modifiers in COVID-19 treatment due to the structu...
Source: Memorias do Instituto Oswaldo Cruz - Category: Infectious Diseases Authors: Tags: Mem Inst Oswaldo Cruz Source Type: research
This article is to examine and summarize the 2 opposing viewpoints and provide guideline recommendations to support the use or discontinuation of ACE inhibitors and ARBs in patients with COVID-19.
Source: Cardiology in Review - Category: Cardiology Tags: Feature Curbside Consult Source Type: research
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