GSE141005 Transcriptome analysis of human colonic IgA+ plasma cell subsets and na ïve B cells

Contributors : Andrea Cerutti ; Giuliana Magri ; Laura ComermaSeries Type : Expression profiling by arrayOrganism : Homo sapiensImmunoglobulin A (IgA) is the most abundant antibody in the intestinal tract. Recent studies show that discrete subsets of gut human plasma cells (PCs) release IgA, which contributes to the maintenance of gut homeostasis. To better characterize the properties of these PC subsets, we performed global transcriptome analysis in na ïve B cells as well as immature CD19+IgA+CD138- PCs, mature CD19+IgA+CD138+ PCs and late CD19-IgA+CD138+ PCs after their purification from human colon samples.

Source: GEO: Gene Expression Omnibus - March 29, 2020 Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research