Propolis extract has bioactivity on the wall and cell membrane of Candida albicans

Publication date: Available online 28 March 2020Source: Journal of EthnopharmacologyAuthor(s): Jakeline L. Corrêa, Flavia F. Veiga, Isabele C. Jarros, Maiara Ignacio Costa, Pamella F. Castilho, Kelly Mari P. de Oliveira, Hélen Cássia Rosseto, Marcos L. Bruschi, Terezinha I.E. Sssssvidzinski, Melyssa Negri
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research

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Abstract Oral problems are common in patients diagnosed with Eating Disorders (ED) and still require better elucidation. We aimed to analyze the prevalence of oral Candida spp in individuals with ED. The sample of the study was comprised of 30 women with purgative habits and 15 without purgative habits. Samples of the oral cavity were collected by sterile cotton swab rubbed on soft tissues and teeth. Yeasts were isolated on Sabouraud dextrose agar. Yeasts were isolated from the oral cavity of 53% of the patients yielding 75 yeast isolates; of these, 43 were identified by conventional mycological methods: C. paraps...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - Category: Tropical Medicine Authors: Tags: Rev Inst Med Trop Sao Paulo Source Type: research
Publication date: Available online 2 June 2020Source: Journal of EthnopharmacologyAuthor(s): Qiandan Miao, Linjing Zhao, Yuting Wang, Fangjia Hao, Peipei Sun, Peng He, Yumin Liu, Jiashuai Huang, Xijian Liu, Xiaohui Liu, Guoying Deng, Hongsen Li, Lingai Li, Yingao Tang, Lixin Wang, Meiqing Feng, Wei Jia
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
The Journal of Organic ChemistryDOI: 10.1021/acs.joc.0c00402
Source: The Journal of Organic Chemistry - Category: Chemistry Authors: Source Type: research
In this study, we screened a library of 1068 FDA-approved drugs to identify hits that exhibit broad-spectrum antifungal activity. Robenidine, an anticoccidial agent which has been widely used to treat coccidian infections of poultry and rabbits, was identified in this screen. Physiological concentration of robenidine (8 μM) was able to significantly inhibit yeast cell growth, filamentation and biofilm formation of Candida albicans – the most extensively studied human fungal pathogen. Moreover, we observed a broad-spectrum antifungal activity of this compound against fluconazole resistant clinical isolates of C. al...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Abstract The dynamic changes of microbiota assessed by high-throughput sequencing and texture properties of handmade cheese were investigated during ripening time. Streptococcus and Lactococcus were found to be the most predominant genera. The proportion of Streptococcus was decreased from 48 to 32% and the proportion of Lactococcus was increased from 41 to 55% with ripening time from 1 to 120 days. Mould and yeast such as Paecilomyces, Candida, Issatchenkia, Rhodotorula, Cryptococcus and Trichosporon were observed. The regression analysis between composition and textural properties indicated that the hardness was...
Source: Archives of Microbiology - Category: Microbiology Authors: Tags: Arch Microbiol Source Type: research
Conditions:   Newborns;   Oral Hygiene;   Candidiasis, Oral;   Behavior Intervention:   Behavioral: oral hygiene Sponsor:   Federal University of the Valleys of Jequitinhonha and Mucuri Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Series Type : Expression profiling by high throughput sequencing ; OtherOrganism : Candida albicans ; Mus musculusThis SuperSeries is composed of the SubSeries listed below.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Other Candida albicans Mus musculus Source Type: research
Contributors : Jessica N Witchley ; Suzanne M NobleSeries Type : OtherOrganism : Candida albicansCandida albicans is a central fungal component of the human gut microbiota and an opportunistic pathogen. Two C. albicans transcription factors, Wor1 and Efg1, control its ability to colonize the mammalian gut. They are also master regulators of an epigenetic switch required for mating. The mammalian gastrointestinal tract is a complex environment difficult to model in vitro. In C. albicans, it is known that environmental signals can dictate the binding targets of these transcription factors. To study the regulation of transcri...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Other Candida albicans Source Type: research
Contributors : Jessica N Witchley ; Suzanne M NobleSeries Type : Expression profiling by high throughput sequencingOrganism : Candida albicans ; Mus musculusWe found through competitive fitness experiments that transcription factors that control the mating regulatory program of C. albicans also control the ability of this fungus to colonize the gastrointestinal tract of mice as a commensal. To determine the role of these TFs, we performed mRNA-seq on luminal contents of C. albicans-colonized mice to determine overall expression patterns that could be correlated to the fitness phenotypes of the mutants in vivo.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Candida albicans Mus musculus Source Type: research
Journal of Natural ProductsDOI: 10.1021/acs.jnatprod.9b00895
Source: Journal of Natural Products - Category: Biochemistry Authors: Source Type: research
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