Polydatin induces apoptosis and autophagy via STAT3 signaling in human osteosarcoma MG-63 cells

In conclusion, these data demonstrated that polydatin induced MG-63 cell death through inducing apoptosis, and autophagy which was mediated via the STAT3 signaling. Therefore, polydatin might be a potential clinical drug in the remedy of osteosarcoma.Graphic abstract
Source: Journal of Natural Medicines - Category: Drugs & Pharmacology Source Type: research