Insulin-producing cells from mesenchymal stromal cells: Protection against cognitive impairment in diabetic rats depends upon implant site
Publication date: Available online 26 March 2020Source: Life SciencesAuthor(s): Krista Minéia Wartchow, Leticia Rodrigues, Lílian Juliana Lissner, Barbara Carolina Federhen, Nicholas Guerini Selistre, Aline Moreira, Carlos-Alberto Gonçalves, Patrícia Sesterheim
CONCLUSIONS: Most studies found GDM screening to be cost-effective, though uncertainties remain due to many factors. The quality assessment identified weaknesses in the economic evaluations in terms of integrating existing data, measuring costs and consequences, analyzing perspectives, and adjusting for uncertainties. PMID: 32448822 [PubMed - as supplied by publisher]
CONCLUSION: The anti-inflammatory property is suggested the mechanism action of PG for protection human lymphocytes against genotoxicity induced by ionizing radiation. PMID: 32448107 [PubMed - as supplied by publisher]
This study aimed at testing the effect of vitamin D supplements on urinary megalin levels in diabetic nephropathy (DN) patients with vitamin D hypovitaminosis. METHODS: A sample of 63 participants with vitamin D deficiency with diabetic nephropathy (DN) were enrolled in the pre-post study; urinary megalin levels with various clinical parameters and serum levels of vitamin D3 were measured and compared to the baseline at 3- and 6-month intervals. RESULTS: Interestingly, a supplementation related increase in serum vitamin D3 levels at 3- and 6- month interventions affected a constellation of ameliorations in the DN p...
This article is part of the theme issue 'Uncertainty quantification in cardiac and cardiovascular modelling and simulation'. PMID: 32448059 [PubMed - in process]
Publication date: Available online 25 May 2020Source: Redox BiologyAuthor(s): Nadezda Apostolova, Francesca Iannantuoni, Aleksandra Gruevska, Jordi Muntane, Milagros Rocha, Victor M. Victor
In conclusion, mitochondrial fatty acid oxidation, and in particular MCAD, contributes to dicarboxylic acid degradation, but feeding dicarboxylic acids induces only the peroxisomal pathway. PMID: 32446361 [PubMed - in process]
Abstract Diabetes has been associated with metabolic disorder, insulin resistance and neuroinflammation. However, the pathogenesis for HFD-induced injury of central nervous system (CNS) is still unclear. Tripartite Motif Containing 13 (TRIM13), also known as RFP2, is a member of TRIM proteins, and is associated with multiple cellular processes, such as apoptosis, survival and inflammation. However, the effects of TRIM13 on brain injury, especially the HFD-induced CNS damage, have not been investigated. To address this issue, the TRIM13flox/flox (fl/fl) mice were produced and then crossed them with Nestin-Cre mice ...
Publication date: Available online 25 May 2020Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Vivek Dave, Rekha Sharma, Chavi Gupta, Srija Sur
Publication date: 15 October 2020Source: Chemical Engineering Journal, Volume 398Author(s): Wen-Lin Hsu, Chiung-Yin Huang, Ying-Pei Hsu, Tsong-Long Hwang, Shih-Hsin Chang, Hay-Yan J. Wang, Li-Ying Feng, Shiow-Jyu Tzou, Kuo-Chen Wei, Hung-Wei Yang
Publication date: Available online 25 May 2020Source: American Journal of Kidney DiseasesAuthor(s): Christie Rampersad, Eyal Kraut, Reid H. Whitlock, Paul Komenda, Vincent Woo, Claudio Rigatto, Navdeep Tangri