Scientists identify gene that first slows, then accelerates, progression of ALS in mice

(The Zuckerman Institute at Columbia University) Columbia scientists have provided new insights into how mutations in a gene called TBK1 cause amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative disease that robs patients of movement, speech and ultimately, their lives. The researchers found that ALS-associated mutations in TBK1 can have both positive and negative effects on the progression of disease in mice genetically modified to have ALS-like symptoms.

Source: EurekAlert! - Biology - March 27, 2020 Category: Biology Source Type: news