Minimizing the Risks of PTSD from the COVID-19 Pandemic

It is a stressful time. Many have begun feeling the emotional and psychological effects of being quarantined. People are being told to stay indoors, to limit leaving their home except for necessities and to skip socializing altogether, if possible. Supermarket shelves are empty; toilet paper and hand sanitizer are sold out. Many communities are placing restrictions on where people can go. Buzzwords like “social distancing” and “martial law” are in the news in recent weeks. Hospitals are overcrowded and staff are overworked. Many playgrounds, amusement parks, hotels and beaches have been closed until further notice. Families are stuck at home, schools have begun distance learning, and most companies are having their employees work from home. We have reached a crisis.  A Global Pandemic  The panic many are experiencing is part of a growing global pandemic. The Centers for Disease Control and Prevention (CDC) identifies COVID-19 as, “a novel respiratory disease that is spread from person to person and may include cough, fever, and shortness of breath.” Severity of symptoms can range from mild to severe, up to and including death for those living with other health conditions. People with diabetes, asthma, young children, or advanced age are at an increased risk for contracting COVID-19.1 In this time of uncertainty, it is important to recognize the impact on mental health including the potential for developing Post-Traumatic Stress Di...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General Mental Health and Wellness PTSD coronavirus COVID-19 quarantine traumatic experience Source Type: blogs

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miR‑205 suppresses cell migration, invasion and EMT of colon cancer by targeting mouse double minute 4. Mol Med Rep. 2020 May 18;: Authors: Fan Y, Wang K Abstract Colon cancer is one of the most frequent malignant tumors, and microRNA (miR)‑205 is involved in the tumor progression. The present study aimed to explore the effects of miR‑205 on human colon cancer and its targeting mechanism. The levels of miR‑205 and mouse double minute 4 (MDM4) were determined via reverse transcription‑quantitative (RT‑q)PCR and western blot analysis. A luciferase activity assay was performed t...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
LncRNA GAS5 suppresses ER stress‑induced apoptosis and inflammation by regulating SERCA2b in HG‑treated retinal epithelial cell. Mol Med Rep. 2020 May 20;: Authors: Jiang L, Wang C, Shen X Abstract Hyperglycemia impairs the retinal functions in patients with diabetic retinopathy (DR). Downregulation of long non‑coding RNA growth arrest‑specific transcript 5 (lncRNA GAS5) expression in diabetes affects glucose intake and insulin signaling. Sarcoplasmic/endoplasmic reticulum Ca2+ ATPase 2 (SERCA2) mediates the regulation of endoplasmic reticulum (ER) stress and apoptosis in high glucose (HG)‑tr...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Transcription factor AP‑2α negatively regulates thymic stromal lymphopoietin expression in respiratory syncytial virus infection. Mol Med Rep. 2020 May 28;: Authors: He J, Cao Q, Feng DD, Chen JH, Zhou GP Abstract Respiratory syncytial virus (RSV) infection enhances the cell‑mediated immune responses of type 2 helper T cells and promotes the progression of allergic inflammation and asthma by producing thymic stromal lymphopoietin (TSLP), especially long isoform TSLP (lfTSLP). However, the role of short isoform TSLP (sfTSLP) in RSV infection remains to be elucidated. The present study was...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Authors: Cui Y, Li Y, Ning J, Mi Y, Wang X, Qiu Z, Li L, Gou X Abstract Mechanical allodynia, which develops in patients of diabetes mellitus as a neuropathic manifestation, remains without an effective treatment. The aim of the present study was to investigate the effects and potential mechanisms underlying resveratrol (RES) in a rat model of streptozocin (STZ)‑induced diabetic mechanical allodynia (DMA). The rat model of DMA was established by the administration of an intraperitoneal injection of STZ. From day 8 post‑STZ injection, rats were administered with an intragastric injection of various doses of RES ...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Effect of IL‑7 on Th17 cell responses in a mouse model of neutrophilic asthma. Mol Med Rep. 2020 May 27;: Authors: Zhang X, Zhang M, Jiang M, Nong G Abstract Neutrophilic asthma (NA) is characterized by neutrophil‑mediated inflammation and the presence of Th17 cells. However, the mechanisms underlying Th17 cell responses in NA remain unknown. The aim of the present study was to examine the effects of interleukin (IL)‑7 on Th17 cell responses in NA. A NA mouse model was sensitized by airway delivery of ovalbumin (OVA) and lipopolysaccharide and challenged with 1% OVA aerosol from day 21 for 3 ...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Diabetic‑induced alterations in hepatic glucose and lipid metabolism: The role of type 1 and type 2 diabetes mellitus (Review). Mol Med Rep. 2020 May 22;: Authors: Jiang S, Young JL, Wang K, Qian Y, Cai L Abstract Diabetes mellitus (DM) is a growing health concern in society. Type 1 and type 2 DM are the two main types of diabetes; both types are chronic diseases that affect glucose metabolism in the body and the impaired regulation of glucose and lipid metabolism promotes the development and progression of DM. During the physiological metabolism process, the liver serves a unique role in glucose and...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
This article proposes strategies to ensure the ongoing effectiveness, efficiency and engagement of lectures transitioning from face-to-face to online delivery. Cognitive learning theory, strategies to promote learner engagement and minimise distraction, and examples of software affordances to support active learning during the lecture are proposed. This enables lecturers to navigate the challenges of lecturing in an online environment and plan fruitful online lectures during this disruptive time. These suggestions will therefore enable HPE to better meet the existing and future needs of regional, rural and remote learners ...
Source: Rural and Remote Health - Category: Rural Health Tags: Rural Remote Health Source Type: research
Conclusions: 60% of patients with MDD and/or AAD had at least one additional NCCD, which significantly increased the economic and humanistic burden. These findings are important for payers and clinicians in making treatment decisions. These results underscore the need for development of multi-pronged interventions which aim to improve quality of life and reduce activity limitations among patients with mental health disorders and NCCDs. PMID: 32468879 [PubMed - as supplied by publisher]
Source: Journal of Medical Economics - Category: Health Management Tags: J Med Econ Source Type: research
Publication date: Available online 29 May 2020Source: The Lancet Respiratory MedicineAuthor(s): James H Hull, Julie K Lloyd, Brendan G Cooper
Source: The Lancet Respiratory Medicine - Category: Respiratory Medicine Source Type: research
Publication date: Available online 29 May 2020Source: The Lancet Respiratory MedicineAuthor(s): Talha Khan Burki
Source: The Lancet Respiratory Medicine - Category: Respiratory Medicine Source Type: research
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