Lifetime patient outcomes and healthcare utilization for Bronchopulmonary dysplasia (BPD) and extreme preterm infants: a microsimulation study

Bronchopulmonary dysplasia (BPD) is among the most severe chronic lung diseases and predominantly affects premature infants. There is a general understanding of BPD ’s significant impact on the short-term outco...
Source: BMC Pediatrics - Category: Pediatrics Authors: Tags: Research article Source Type: research

Related Links:

.
Source: Journal of Maternal-Fetal and Neonatal Medicine - Category: Perinatology & Neonatology Authors: Source Type: research
Abstract RATIONALE: Bronchopulmonary dysplasia is a heterogeneous lung disease characterized by regions of cysts and fibrosis, but methods for evaluating lung function are limited to whole lung rather than specific regions of interest. OBJECTIVE: Respiratory-gated, ultrashort echo time MRI was used to test the hypothesis that cystic regions of the lung will exhibit a quantifiable tidal volume (TV) that will correlate with ventilator settings and clinical outcomes. METHODS: MRI of 17 non-sedated, quiet-breathing, severe bronchopulmonary dysplasia infants were reconstructed into end-inspiration and end-exp...
Source: American Journal of Respiratory and Critical Care Medicine - Category: Respiratory Medicine Authors: Tags: Am J Respir Crit Care Med Source Type: research
Authors: PMID: 32454498 [PubMed - as supplied by publisher]
Source: Neonatology - Category: Perinatology & Neonatology Tags: Neonatology Source Type: research
CONCLUSION: Up to 49% of NICUs had low PNC use and low BPD rates, without a difference in mortality. Infants hospitalized in NICUs with a stated policy of low PNC use did not have an increased risk of BPD. PMID: 32454484 [PubMed - as supplied by publisher]
Source: Neonatology - Category: Perinatology & Neonatology Authors: Tags: Neonatology Source Type: research
An amendment to this paper has been published and can be accessed via the original article.
Source: Respiratory Research - Category: Respiratory Medicine Authors: Tags: Correction Source Type: research
Conclusion Infants with BPD are prone to develop gut dysbiosis in early life. A higher severity of illness and treatment intensity may indicate a higher risk of disrupting an anaerobic environment in the gut during the first month of life. Key Points [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: American Journal of Perinatology - Category: Perinatology & Neonatology Authors: Tags: Original Article Source Type: research
This study aimed to review early bCPAP pressures and bCPAP failure with the RAM cannula interface over a 6-year period. Study Design Retrospective, single-center study of infants delivered
Source: American Journal of Perinatology - Category: Perinatology & Neonatology Authors: Tags: Original Article Source Type: research
Am J Perinatol DOI: 10.1055/s-0040-1710353 Objective We aimed to determine the independent effect of maternal antepartum hemorrhage (APH) on mortality and major neonatal morbidities among very low birth weight (VLBW), very preterm infants. Study design A population-based cohort study of VLBW singleton infants born at 24 to 31 weeks of gestation between 1995 and 2016 was performed. Infants born with the following pregnancy associated complications were excluded: maternal hypertensive disorders, prolonged rupture of membranes, amnionitis, maternal diabetes, and small for gestational age. APH included hemorrha...
Source: American Journal of Perinatology - Category: Perinatology & Neonatology Authors: Tags: Original Article Source Type: research
Abstract BACKGROUND: Bronchopulmonary dysplasia (BPD) is the most common respiratory disorder in extremely low birth weight infants. Although most BPD symptoms improve, some late complications exist, even with regular treatment. Gastroesophageal reflux (GER), also common in extremely premature infants, may be related to many cardiorespiratory symptoms. However, the potential of GER as a risk factor for late complications associated with BPD is still unclear. RESEARCH QUESTION: Does GER increase the risk of late complications of BPD in infants? STUDY DESIGN: and Methods: A multi-center prospective cohort ...
Source: Chest - Category: Respiratory Medicine Authors: Tags: Chest Source Type: research
Abstract Within the human lung, mast cells typically reside adjacent to the conducting airway, and assume a "mucosal" phenotype (MCT). In rare pathological conditions, "connective tissue" phenotype mast cells (MCTC) can be found in the lung parenchyma. MCTC accumulate in the lungs of infants with severe bronchopulmonary dysplasia (BPD), a chronic lung disease associated with preterm birth, which is characterized by pulmonary vascular dysmorphia. The human LUVA mast cell line was used to model MCTC or MCT. The ability of MCTC to affect vascular organization during fetal lung development was test...
Source: The American Journal of Pathology - Category: Pathology Authors: Tags: Am J Pathol Source Type: research
More News: Bronchopulmonary Dysplasia | Pediatrics | Study