Covariate adjusted reanalysis of the I-Preserve trial

ConclusionAdjusting for imbalances in baseline variables that influence outcomes (or the response to therapy or both) can improve the power around the estimate of the effect of treatment and may alter its statistical significance. Along with the CHARM-Preserved results, these findings suggest that angiotensin-receptor blockers may have a modest effect in HFpEF.
Source: Clinical Research in Cardiology - Category: Cardiology Source Type: research