Induction of PD-L1 by Nitric Oxide via JNK Activation in A172 Glioblastoma Cells.

We examined the effects of NOC-18, an NO donor, on the expression of PD-L1 in A172 glioblastoma cells. NOC-18 increased PD-L1 expression in A172 glioblastoma cells. Moreover, this increase is regulated via the JNK pathway. PMID: 32201424 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32201424?dopt=Abstract

Source: Biological and Pharmaceutical Bulletin - March 19, 2020 Category: Drugs & Pharmacology Authors: Kiriyama Y, Tani A, Kadoya M, Okamoto R, Nochi H Tags: Biol Pharm Bull Source Type: research