Development and characterization of a tissue mimicking psyllium husk gelatin phantom for ultrasound and magnetic resonance imaging.
Conclusions: The presented dual-use tissue-mimicking phantom is easy to manufacture and can be used to compare and evaluate US-guided and MR-guided HIFU imaging protocols. PMID: 32204632 [PubMed - in process]
Authors: Guo X, Zhu H, Zhou K, Jin C, Yang Y, Zhang J, Yang W, Ran L, Dimitrov DD Abstract The present study aimed to evaluate the safety of high-intensity focused ultrasound (HIFU) treatment on peripancreatic arterial and venous blood vessels in patients with pancreatic cancer. This trial included 15 patients with pancreatic cancer (9 females and 6 males; age, 39-81 years; median age, 62 years). All patients underwent preoperative computed tomography (CT) or magnetic resonance imaging (MRI) and color Doppler flow imaging (CDFI) to assess the vascular hemodynamics of peripancreatic arterial and venous blood vessels...
Conclusion: Our study provides preliminary support for the safety and efficacy of MRgFUS CLT, a histologically and pathophysiologically based medial thalamotomy against chronic therapy-resistant trigeminal neuralgia.
CONCLUSION: The preliminary results demonstrated that volumetric MRI-guided HIFU therapy for the treatment of symptomatic leiomyomas in ASEAN patients appears to be clinically acceptable with regard to treatment effectiveness and safety. PMID: 32209511 [PubMed - as supplied by publisher]
Authors: Zhang YJ, Xiao ZB, Lv FR, Sheng B, Li J, Zheng YN, Lv FJ, Chen JY Abstract Purpose: To evaluate endopelvic fascial swelling in patients with uterine fibroids after high-intensity focused ultrasound (HIFU) ablation on magnetic resonance imaging (MRI) and investigate the factors that influence endopelvic fascial swelling.Methods: MRI and clinical data from 188 patients with uterine fibroids who were treated with HIFU were analyzed retrospectively. The patients were divided into a fascial swelling group and a non-swelling group, and the degree of swelling was graded. Fascial swelling was set as the dependent ...
This article reviews the principles and biologic effects of high-intensity focused ultrasound, provides an overview of the MRgFUS treatment system and use of magnetic resonance thermometry, discusses the use of MRgFUS for the treatment of extra-abdominal desmoid tumors, and provides several case examples.
Conclusion: MR-HIFU delivery during forced breath holds enables stable control of mild hyperthermia in targets adjacent to moving anatomical structures. PMID: 31707872 [PubMed - in process]
Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b07591
Abstract Periodic high-intensity focused ultrasound modulation of a nanoparticle generates reversible MRI T1 relaxivity changes at the 1.5 mm3 focal point causing periodic T1-weighted signal changes. Fourier analysis extracts signal changes at the modulation frequency, and a modulation enhancement map spotlights the precise region of interest by increasing contrast almost 100-fold. PMID: 31393462 [PubMed - as supplied by publisher]
ConclusionsAblations yielding coagulative necrosis of liver tissue can be performed adjacent to large hepatic vessels while keeping the vessel walls intact. This indicates that perivascular tumor ablation in the liver is feasible using MRgHIFU.Key Points•High-intensity focused ultrasound ablation is a non-invasive treatment modality that can be used for treatment of liver tumors.•This study shows that ablations of liver tissue can be performed adjacent to large hepatic vessels in an experimental setting.•Liver tumors close to large vessels can potentially be treated using this modality.
Chem. Commun., 2019, Accepted Manuscript DOI: 10.1039/C9CC03701B, CommunicationTian Deng, Le Zhang, Holden H. Wu, Jeffrey I. Zink Periodic high-intensity focused ultrasound modulation of a nanoparticle generates reversible MRI T1 relaxivity changes at the 1.5 mm3 focal point causing periodic T1-weighted signal changes. Fourier analysis extracts signal changes... The content of this RSS Feed (c) The Royal Society of Chemistry