Loneliness, social isolation, and social reward in the aging population: examining interventions, mechanisms, and outcomes

The global epidemic of loneliness and social isolation has health consequences that rival those of smoking and obesity. Older adults are at particularly high risk for loneliness, due to age-related declines in functioning and reduction in social networks. There is a need to further understand the effects of loneliness on cognitive, mental, and physical health in older adults; identify the underlying neural and behavioral mechanisms of social isolation; and develop interventions targeting deficits in these mechanisms.
Source: The American Journal of Geriatric Psychiatry - Category: Geriatrics Authors: Tags: Session 312 Source Type: research

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This study aimed to present the longitudinal course of height, weight, and body mass index (BMI) of children from IBD diagnosis to 18  months of follow-up, and to describe the impact of BMI on the clinical course of the disease. One hundred and fifty-two children were identified, of whom 85 had Crohn’s disease (CD) and 67 had ulcerative colitis (UC). During a median (interquartile range) follow-up of 2.95 (1.73–4.5) years, w eight and BMI Z-scores increased in the first 18 months since diagnosis in both the CD (P 
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research
AbstractPurpose of ReviewIn the treatment of epidemic obesity and metabolic disorders, conservative approaches often fail to achieve the treatment goal in patients with very high BMI. To date, bariatric surgery accomplishes the most sustainable results in patients with morbid obesity. This leads to a treatment gap for lower and middle classes of obesity defined by BMI. Primary endoscopic procedures, which are less invasive than surgery, may be able to sufficiently fill this gap. Furthermore, secondary endoscopic procedures have developed into an essential addition regarding complication management of bariatric surgeries. T...
Source: Current Obesity Reports - Category: Eating Disorders & Weight Management Source Type: research
This report presents the case of a 55-year-old woman with a previous Roux-en-Y gastric bypass who was shown by endoscopy to have an invasive adenocarcinoma located in the distal thoracic esophagus. This necessitated an excision of the thoracic esophagus and the gastric pouch. A laparoscopic and thoracoscopic Ivor-Lewis esophagogastrectomy was performed for this complex patient with esophageal adenocarcinoma. The remnant stomach was fashioned into a gastric conduit using a 60-mm linear stapler with a staple height of 4.1 mm (Echelon, Ethicon Endosurgery, Blue Ash, OH). The reconstruction was performed using a 25-mm Orvil (C...
Source: Annals of Surgical Oncology - Category: Cancer & Oncology Source Type: research
MONDAY, June 1, 2020 -- As if the childhood obesity epidemic isn't bad enough, new research warns that over one million more American boys and girls stand to become obese if coronavirus-related school closures continue through the end of the...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Diabetes mellitus is the 7th leading cause of death worldwide according to the World Health Organization. The rate of obesity has reached epidemic proportions in westernized countries. Non-alcoholic fatty liver disease (NAFLD) is associated with diabetes and obesity and is currently a leading etiology for liver transplantation in the United States. The duodenum plays an important role in nutrient absorption and glucose metabolism. Duodenal mucosal resurfacing (DMR) is a novel endoscopic technique of hydrothermal ablation of the duodenal mucosa potentially improving glycemic control.
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Poster abstracts Source Type: research
The global epidemic of overweight and obesity – termed “globesity”, is an escalating public health problem. It is crucial that bariatric endoscopists innovate, and procedures evolve to produce more effective and less invasive therapies. Endoscopic Sleeve Gastroplasty (ESG) is an incisionless, minimally invasive Endoscopic Bariatric Therap y (EBT) that involves remodeling the greater curvature of the stomach by placement of full-thickness sutures. Percent total body weight loss (%TBWL) at 12 months following ESG is 16.5% compared to 3-7.5% with weight loss medications.
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Poster abstracts Source Type: research
In a time of obesity epidemic, bariatric surgical treatment by Roux-en-Y gastric bypass (RYGB) has become the standard of care. To date, no single universal algorithmic approach for ERCP has been identified as preferential for these patients. Our institutional protocol has been to use the double balloon enteroscopy – assisted ERCP (DBE-ERCP) as first line and to reserve EUS-directed transgastric ERCP (EDGE) for cases in which adjunctive techniques are needed that cannot be performed through an enteroscope.
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Poster abstracts Source Type: research
The heart failure syndrome has first been described as an emerging epidemic about 25  years ago. Today, because of a growing and ageing population, the total number of heart failure patients still continues to rise. However, the case mix of heart failure seems to be evolving. Incidence has stabilized and may even be decreasing in some populations, but alarming opposite trends have been observed in the relatively young, possibly related to an increase in obesity. In addition, a clear transition towards heart failure with a preserved ejection fraction has occurred. Although this transition is partially artificial, due...
Source: European Journal of Heart Failure - Category: Cardiology Authors: Tags: Review Source Type: research
anger J Abstract The worldwide epidemic of overweight and obesity has led to an increase in associated metabolic comorbidities. Obesity induces chronic low-grade inflammation in white adipose tissue (WAT). However, the function and regulation of both innate and adaptive immune cells in human WAT under conditions of obesity and calorie restriction (CR) is not fully understood yet. Using a randomized interventional design, we investigated postmenopausal overweight or obese female subjects who either underwent CR for 3 mo followed by a 4-wk phase of weight maintenance or had to maintain a stable weight over the whole...
Source: Journal of Immunology - Category: Allergy & Immunology Authors: Tags: J Immunol Source Type: research
Authors: Ng CM, Satvinder K, Koo HC, Yap RWK, Mukhtar F Abstract Involving school-age children in the preparation of healthy meals is shown to be associated with positive eating behavior. Yet, it remains unclear whether this can extend to their nutritional status. The present study aimed to determine the association of school-age children's psychosocial factors (knowledge, attitude, practice, self-efficacy) towards healthy meal preparation with their nutritional status (BMI-for-age, waist circumference, body fat percentage). Stratified random sampling was used to select primary schools (n = 8) in Kuala L...
Source: International Journal for Vitamin and Nutrition Research - Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research
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