Personalized medicine and breast cancer: anticipatory medicine, prognostic evaluation and therapeutic targeting.

Personalized medicine and breast cancer: anticipatory medicine, prognostic evaluation and therapeutic targeting.
Bull Cancer. 2013 Nov 13;
Authors: Gonçalves A, Moretta J, Eisinger F, Bertucci F
Abstract
Breast cancer is now considered as a large collection of distinct biological entities, the management of which is increasingly personalized. Personalized medicine - defined as a medicine, which uses molecular profiles, notably genetic profiles, from patients and/or tumors to tailor therapeutic decisions - is now introduced in the management of breast cancer at any stages: screening and prevention of hereditary forms, prognostic and predictive evaluation of early breast cancer, and, more recently, novel clinical trials in advanced breast cancer, where genetic characterization of tumor tissue based on genomics, including next-generation sequencing tools, is used to drive specific therapeutic targeting.
PMID: 24225763 [PubMed - as supplied by publisher]

Source: Bulletin du Cancer - November 13, 2013 Category: Cancer & Oncology Authors: Gonçalves A, Moretta J, Eisinger F, Bertucci F Tags: Bull Cancer Source Type: research