D-Dimer Level Predicts Angiographic No-Reflow Phenomenon After Percutaneous Coronary Intervention Within 2 –7 Days of Symptom Onset in Patients with ST-Segment Elevation Myocardial Infarction

This study retrospectively enrolled 229 consecutive patients who had pPCI for acute STEMI within 2–7 days of symptom onset between January 2008 and December 2018. Patients were divided into no-reflow group (TIMI flow grade 0–2) and reflow group (TIMI flow grade 3). Predict ors of no-reflow were assessed by univariate and multivariate binary logistic regression analyses. Plasma D-dimer level can independently predict no-reflow in patients with STEMI who had pPCI within 2–7 days of symptom onset (OR 2.52 per 1 mg/L increase, 95% CI 1.16–5.47,p = 0.019). This finding indicated that pPCI may be safe and feasible for STEMI patients within 2–7 days of symptom onset with low D-dimer level.Graphical AbstractPlasma D-dimer level can independently predict no-reflow in patients with STEMI who had pPCI within 2 –7 days of symptom onset. pPCI may be safe and feasible for STEMI patients within 2–7 days of symptom onset with low D-dimer level.
Source: Journal of Cardiovascular Translational Research - Category: Cardiology Source Type: research