Kinetic analysis of HER2-binding ABY-025 Affibody molecule using dynamic PET in patients with metastatic breast cancer

Conclusion68Ga-ABY-025 binding in HER2-positive metastases was well characterized by irreversible two-tissue compartment model whereinKi highly correlated with SUVs at 2 and 4  h. Dynamic scanning with parametric image formation can be used to evaluate metastatic HER2 expression accurately.
Source: EJNMMI Research - Category: Radiology Source Type: research