Knockdown of miR-124 reduces depression-like behavior in rats by targeting CREB1 and BDNF.

CONCLUSION: Knockdown of miR-124 can improve depression-like behavior in CUMS-induced depressive rats, which may be related at least in part to the up-regulation of CREB1 and BDNF expression in the hippocampus. PMID: 32189593 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32189593?dopt=Abstract

Source: Current Neurovascular Research - March 18, 2020 Category: Neurology Authors: Yang W, Liu M, Zhang Q, Zhang J, Chen J, Suo L, Chen Q Tags: Curr Neurovasc Res Source Type: research