Shear Stress-Induced miR-143-3p in Collateral Arteries Contributes to Outward Vessel Growth by Targeting Collagen V- α2.

CONCLUSIONS: These results indicate that the increased miR-143-3p expression in response to FSS might contribute to the reorganization of the extracellular matrix, which is important for vascular remodeling processes, by inhibiting collagen V-α2 biosynthesis (Visual Overview).
PMID: 32188276 [PubMed - as supplied by publisher]

Source: Arteriosclerosis, Thrombosis and Vascular Biology - March 18, 2020 Category: Cardiology Authors: Troidl K, Hammerschick T, Albarran-Juarez J, Jung G, Schierling W, Tonack S, Krüger M, Matuschke B, Troidl C, Schaper W, Schmitz-Rixen T, Preissner KT, Fischer S Tags: Arterioscler Thromb Vasc Biol Source Type: research