“Is bariatric surgery resolving NAFLD via microbiota-mediated bile acid ratio reversal? A comprehensive review.”

Non-alcoholic fatty liver disease (NAFLD) is considered the hepatic manifestation of the metabolic syndrome, as it is closely related to obesity, dyslipidemia and insulin resistance [1]. Accordingly, the prevalence of NAFLD and non-alcoholic steatohepatitis (NASH), NAFLD ’s later evolutive stage, are increasing at the same pace as obesity becomes a global epidemic. In fact, today, NAFLD is considered to be the number one cause of chronic liver disease worldwide [2-4]. As no specific drugs have yet been approved for NAFLD, at present, the only effective treatment i s weight loss through diet and exercise.

Source: Surgery for Obesity and Related Diseases - March 19, 2020 Category: Surgery Authors: Eider Talavera-Urquijo, Marc Beisani, Jos é M. Balibrea, John C. Alverdy Tags: Review articles Source Type: research