Anesthetic Management of a Patient With Systemic Sclerosis and Microstomia.
Anesthetic Management of a Patient With Systemic Sclerosis and Microstomia. Anesth Prog. 2020;67(1):28-34 Authors: Shionoya Y, Kamiga H, Tsujimoto G, Nakamura E, Nakamura K, Sunada K Abstract Systemic sclerosis (SSc) is an autoimmune disease that can cause fibrosis in vital organs, often resulting in damage to the skin, blood vessels, gastrointestinal system, lungs, heart, and/or kidneys. Patients with SSc are also likely to develop microstomia, which can render dental treatment difficult and painful, thereby necessitating advanced anesthetic management. This is a case report of a 61-year-old woman with a history of SSc with microstomia, interstitial pneumonia, and gastroesophageal reflux disease in whom intravenous moderate sedation was performed using a combination of dexmedetomidine and ketamine for dental extractions. Both anesthetic agents are known to have analgesic effects while minimizing respiratory depression. Consequently, the increased discomfort caused by opening the patient's mouth and stretching the buccal mucosa was sufficiently managed, permitting an increase in maximum interincisal opening and completion of treatment without complications. Patients with SSc present with serious comorbidities that can negatively impact anesthetic management, so the implementation of an anesthetic plan that takes such risks into account is required. Furthermore, emergency airway management is likely to be difficult in patients with microstomia. For intrave...
Publication date: Available online 30 May 2020Source: European Journal of Integrative MedicineAuthor(s): Jingyi Shao, Lingming Zhou, Tianyu Shao, Minrui Ding, Zhuqing Jin
Publication date: Available online 30 May 2020Source: Trends in Anaesthesia and Critical CareAuthor(s): Julian Kunze, Sebastian Fritsch, Arne Peine, Oliver Maaßen, Gernot Marx, Johannes Bickenbach
Publication date: Available online 22 April 2020Source: Best Practice &Research Clinical AnaesthesiologyAuthor(s): Harish Siddaiah, Shilpadevi Patil, Anitha Shelvan, Kenneth Philip Ehrhardt, Cain W. Stark, Kenneth Ulicny, Sasha Ridgell, Austin Howe, Elyse M. Cornett, Richard D. Urman, Alan D. Kaye
CONCLUSIONS: Further studies are required in order to establish the complicated association between SARS-CoV-2 infection and its effects on the cardiovascular system. Our knowledge regarding diagnostic approaches, therapeutic management and preventive measures is constantly enriched throughout an abundance of ongoing research in the respective fields. PMID: 32472990 [PubMed - as supplied by publisher]
Publication date: Available online 30 May 2020Source: Progress in Neuro-Psychopharmacology and Biological PsychiatryAuthor(s): Gianluca Serafini, Giovanna Canepa, Andrea Aguglia, Andrea Amerio, Davide Bianchi, Magnani, Bernardo Dell'Osso, Maurizio Pompili, Paul B. Fitzgerald, Mario Amore
Conclusions: Within our study population, pemphigus predominately affected females, and the most common clinical variant was PV, a subtype that frequently occurs in middle-aged individuals. MCP was the most common clinical pattern. Although MCP and higher doses of corticosteroids were needed to control pemphigus, they did not seem to influence the prognosis. PMID: 32467679 [PubMed]
CONCLUSIONS: This unprecedented crisis may interact with certain dimensions of the suicidal process. However, it is time to innovate. Several suicide prevention tools all have their place in new modes of care and should be tested on a large scale. PMID: 32471707 [PubMed - as supplied by publisher]
Propofol suppresses the progression of non‑small cell lung cancer via downregulation of the miR‑21‑5p/MAPK10 axis. Oncol Rep. 2020 May 21;: Authors: Wu X, Li X, Xu G Abstract Non‑small cell lung cancer (NSCLC) accounts for>80% of lung cancer cases and is the leading cause of cancer‑associated mortality worldwide. Propofol is an anesthetic drug frequently used during tumor resection. It is also known to exert inhibitory effects on cancer. Although the role of propofol in NSCLC has been reported, its underlying mechanisms remain unknown. The present study aimed therefore to investigate the m...
Authors: Rahimian R, Fakhfouri G, Zirak MR PMID: 32470874 [PubMed - as supplied by publisher]