Systematic review of Photobiomodulation Therapy (PBMT) on the experimental calcaneal tendon injury in rats

This study was conducted in accordance with the guidelines of the Preferred Reporting Items for Meta‐Analysis, and PubMed and MedLine databases were accessed to search eligible studies published in English. The search terms were: "Achilles tendon" or "Calcaneal tendon" or "tendon injuries" or "soft tissue injuries" and "tendinopathy" or "tendinitis" and "low‐level light therapy" or "low‐level laser therapy" or "low intensity power therapy" or "light‐emitting diode" or photobiomodulation". The SYRCLE risks of bias (Sistematic Review Center for Laboratory Animal Experimentation) was used to assess the risk of bias for selected studies. A total of 225 studies were found based on the descriptors used, and only 33 studies were eligible. Light parameters identified per point of irradiation were approximately 60 mW (continuous mode at infrared spectra), 2 W/cm2, 2 J and 45 J/cm2. Light parameters at red spectra, continuous versus pulsed mode, PBMT combined or compared with other therapies such as ultrasound, and studies using unhealthy rats (ovariectomized and/or diabetic models) were also identified and grouped according these similarities. The main effects found were decreased inflammatory markers and signs of inflammatory process. PBMT (laser/LED) has positive effects in reducing the inflammatory and time for tissue repair in animal models of tendon injury and/or tendinitis using parameters identified.
Source: Photochemistry and Photobiology - Category: Science Authors: Tags: RESEARCH ARTICLE Source Type: research