Do the instructions for use matter?

Almost since inception, endovascular aneurysm repair (EVAR) was felt to be a less invasive way to treat abdominal aortic aneurysm in higher risk patients, many of whom would not be candidates for open repair. Graft manufacturers are required to submit instructions for use (IFU) as part of the approval process. Physicians are not required to follow the IFU, but it makes sense to adhere to it as much as feasible to allow maximal benefit to the patient. The meta-analysis by Antoniou et  al1 looks at 4500 patients treated with EVAR between 2006 and 2015.
Source: Journal of Vascular Surgery - Category: Surgery Authors: Tags: Invited commentary Source Type: research