Geranylgeraniol suppresses the viability of human prostate cancer cells and HMG CoA reductase

Researchers at Texas Woman's University have shown that a diterpene geranylgeraniol found in linseed oil, Cedrela toona wood oil, sucupira branca fruit oil and more recently, annatto seed oil, suppressed the viability of human DU145 prostate carcinoma cells via cell cycle arrest at the G1 phase and the initiation of apoptosis. This finding, reported in the November 2013 issue of Experimental Biology and Medicine, supplies recent evidence supporting the tumor-suppressive potential of dietary isoprenoids, a class of phytochemicals encompassing ~55,000 mevalonate-derived secondary metabolites.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Prostate / Prostate Cancer Source Type: news